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将公共卫生干预措施置于消除地方病的背景下:斯里兰卡成功消除疟疾的回顾带来的新启示

Contextualizing Public Health Interventions in Eliminating Endemic Diseases: New Lessons From a Review of Sri Lanka's Success in Eliminating Malaria.

作者信息

Wisden Benjamin H, Hewadikaram Madhavi, Dissanayake Uthsara, Maxwell Curtis, Gunasekera Poorna, Danso Samuel, Katuwavila Nuwanthi P

机构信息

University of Plymouth, Plymouth, UK.

National School of Business Management, Colombo, Sri Lanka.

出版信息

Inquiry. 2024 Jan-Dec;61:469580241308443. doi: 10.1177/00469580241308443.

Abstract

Malaria remains a major global public health issue, demanding significant resources from governments, health organizations, and international organizations toward its elimination as an endemic disease. In 2016, Sri Lanka achieved the remarkable feat of being declared "malaria free" by the World Health Organisation (WHO), after over a century of indigenous disease. To identify significant lessons of global importance in eliminating endemic malaria by reviewing literature on Sri Lanka's successful elimination campaign. The history of malaria in Sri Lanka highlights the nation's journey from widespread malaria prevalence to achieving malaria-free status in 2016. Key interventions, such as the establishment of the Anti-Malaria Campaign in 1911, the introduction of Dichloro-Diphenyl-Trichloroethane (DDT) in 1946, and the launch of a malaria eradication program in 1958, played crucial roles in controlling the disease. However, challenges such as insecticide resistance, environmental changes, and civil war periodically caused resurgences. The 21st century saw intensified efforts in surveillance, vector control, and community engagement, culminating in the elimination of indigenous malaria cases in 2012. Despite this success, the risk of reintroduction from imported cases remains, necessitating ongoing vigilance and preventive measures. The case study of Sri Lanka is remarkable, and can provide valuable insight for stakeholders involved in eradicating malaria, with the caveat that this case is further evidence of the differential nature of malaria transmission worldwide.

摘要

疟疾仍然是一个重大的全球公共卫生问题,需要政府、卫生组织和国际组织投入大量资源以将其作为一种地方病予以消除。2016年,在经历了一个多世纪的本土疟疾流行之后,斯里兰卡实现了一项非凡成就,被世界卫生组织(WHO)宣布为“无疟疾”国家。通过回顾斯里兰卡成功消除疟疾运动的相关文献,以确定在消除地方性疟疾方面具有全球重要意义的显著经验教训。斯里兰卡的疟疾历史凸显了该国从疟疾广泛流行到2016年实现无疟疾状态的历程。关键干预措施,如1911年设立抗疟疾运动、1946年引入二氯二苯三氯乙烷(DDT)以及1958年启动疟疾根除计划,在控制该疾病方面发挥了关键作用。然而,诸如杀虫剂抗性、环境变化和内战等挑战不时导致疫情复发。21世纪,在监测、病媒控制和社区参与方面加大了力度,最终在2012年消除了本土疟疾病例。尽管取得了这一成功,但输入性病例再次引入的风险依然存在,因此需要持续保持警惕并采取预防措施。斯里兰卡的案例很突出,可为参与疟疾根除工作的利益相关者提供宝贵的见解,但需注意的是,该案例进一步证明了全球疟疾传播的差异性。

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