Pezdirc Neža, Stopar Pintarič Tatjana, Lučovnik Miha
Department of Perinatology, Division of Obstetrics and Gynecology, University Medical Centre Ljubljana, Ljubljana, Slovenia; Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Department of Anaesthesiology and Surgical Intensive Care, University Medical Centre Ljubljana, Ljubljana, Slovenia; Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Biomol Biomed. 2025 May 8;25(7):1517-1521. doi: 10.17305/bb.2024.11679.
Severe maternal morbidity is a major global health concern, and early identification of at-risk postpartum women is essential to improving outcomes. We aimed to compare the predictive values of the Modified Early Obstetric Warning System (MEOWS) versus the non-obstetric general Early Warning System (EWS) for predicting severe maternal morbidity in postpartum women. We retrospectively reviewed hospital documentation of 723 postpartum women admitted to the obstetric high dependency unit between October 2020 and March 2021. Severe maternal morbidity was defined using the American College of Obstetricians and Gynecologists' criteria. We assessed the sensitivity, specificity, positive and negative predictive values, as well as positive and negative likelihood ratios, of the MEOWS and the EWS for predicting severe postpartum maternal morbidity. Twenty-four (3.3%) women included in the study met the criteria for severe maternal morbidity. Hypertensive complications and obstetric haemorrhage were the most prevalent causes of maternal morbidity. The sensitivity of the MEOWS was 92%, specificity 62%, positive predictive value 8%, and negative predictive value 100%. The positive likelihood ratio was 2.4, while the negative likelihood ratio was 0.1. In comparison, the EWS had a sensitivity of 63%, specificity of 66%, positive predictive value of 6%, and negative predictive value of 98%. The positive likelihood ratio for the EWS was 1.8, and the negative likelihood ratio was 0.6. The obstetric-specific early warning system proved to be superior for the early prediction of severe postpartum maternal morbidity compared to the general non-obstetric warning system.
严重孕产妇发病是一个重大的全球健康问题,早期识别产后高危妇女对于改善结局至关重要。我们旨在比较改良早期产科预警系统(MEOWS)与非产科通用早期预警系统(EWS)对产后妇女严重孕产妇发病的预测价值。我们回顾性分析了2020年10月至2021年3月期间入住产科高依赖病房的723名产后妇女的医院记录。采用美国妇产科医师学会的标准定义严重孕产妇发病。我们评估了MEOWS和EWS预测产后严重孕产妇发病的敏感性、特异性、阳性和阴性预测值以及阳性和阴性似然比。纳入研究的24名(3.3%)妇女符合严重孕产妇发病标准。高血压并发症和产科出血是孕产妇发病的最常见原因。MEOWS的敏感性为92%,特异性为62%,阳性预测值为8%,阴性预测值为100%。阳性似然比为2.4,阴性似然比为0.1。相比之下,EWS的敏感性为63%,特异性为66%,阳性预测值为6%,阴性预测值为98%。EWS的阳性似然比为1.8,阴性似然比为0.6。与通用非产科预警系统相比,产科特异性早期预警系统在早期预测产后严重孕产妇发病方面表现更优。