Kumar Arjun B, Khan Usama, Limaye Kaustubh
Department of Neurology, Indiana University School of Medicine, Indianapolis, IN, USA.
Department of Neurology, Neurological Surgery and Radiology, Indiana University School of Medicine, Indianapolis, IN, USA.
Interv Neuroradiol. 2024 Dec 18:15910199241308318. doi: 10.1177/15910199241308318.
Mechanical thrombectomy has become the cornerstone to achieve reperfusion in large vessel occlusion causing acute ischemic stroke. Since the advent of intracranial thrombectomy, the procedural setup has been to deliver aspiration catheter over microwire and microcatheter to the intracranial occlusion (ADAPT) or to deliver the stent-retriever through the microcatheter (SOLUMBRA) to perform thrombectomy. In both these techniques the quintessential aspect is crossing the clot/thrombus, which increases the chances of clot fragmentation or disruption. We demonstrate delivering an ultra-large bore (Sofia 0.088, Microvention, Aliso Viejo, CA, USA) to the intracranial occlusion over a macrowire (Aristotle Colossus OD: 0.035' × 200 cm, Scientia Vascular, UT, USA) alone with no use of microcatheter or microwire. The utilization of macrowire to perform thrombectomy provides enough support to guide the large or ultra large bore catheter to the clot interface without the need to cross the clot. As this technique involves no crossing of clot it prevents clot disruption and distal embolization. There are other possible benefits which are under study in MINT Registry and include making thrombectomy more time and cost efficient.
机械取栓术已成为实现大血管闭塞所致急性缺血性卒中再灌注的基石。自颅内取栓术问世以来,手术操作通常是通过微导丝和微导管将抽吸导管送至颅内闭塞部位(ADAPT技术),或通过微导管送入支架取栓器(SOLUMBRA技术)来进行取栓。在这两种技术中,关键环节都是穿过血栓,这增加了血栓破碎或断裂的几率。我们展示了仅通过一根粗导丝(亚里士多德巨像型,外径:0.035英寸×200厘米,美国犹他州Scientia Vascular公司)将超大口径导管(索非亚0.088,美国加利福尼亚州阿利索维耶荷市Microvention公司)送至颅内闭塞部位,而不使用微导管或微导丝。利用粗导丝进行取栓可提供足够的支撑,将大口径或超大口径导管引导至血栓界面,而无需穿过血栓。由于该技术不涉及穿过血栓,可防止血栓破裂和远端栓塞。MINT注册研究正在研究其他可能的益处,包括提高取栓的效率和降低成本。