Psychiatry and Psychology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Yazd Cardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Arch Iran Med. 2019 Oct 1;22(10):546-553.
There is no clear picture regarding the prevalence rates of autism and its comorbidities among Iranian children and adolescents. The present study aimed to estimate these rates as part of a large national population-based study on epidemiology of psychiatric disorders in Iranian children and adolescents.
The total sample consisted of 31000 children and adolescents between 6 to 18 years of age. The Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Present and Life time version (K-SADS-PL) was used as the diagnostic tool.
The prevalence of autism in the total sample is equal to 0.1% (10 per 10000), with a 2:1 male-to-female ratio. In total, 86% of people with autism had at least one comorbid condition. Intellectual disability, epilepsy, enuresis and attention deficit and hyperactivity disorder (ADHD) with prevalence rates of 70.3%, 29.7%, 27% and 21.62%, respectively, were the most prevalent comorbid conditions in people with autism. Maternal personality disorders were also shown to be associated with increasing risk of autism.
The present study shows high prevalence rates for autism and its comorbid conditions among Iranian children and adolescents. It also reveals that there is a relationship between some maternal psychiatric disorders and the risk of autism.
伊朗儿童和青少年自闭症及其共病的流行率尚不清楚。本研究旨在估计这些比率，这是伊朗儿童和青少年精神障碍流行病学的一项大型全国性基于人群的研究的一部分。
总样本由 31000 名 6 至 18 岁的儿童和青少年组成。使用儿童心境障碍和精神分裂症诊断性会谈表修订版（K-SADS-PL）作为诊断工具。
总样本中自闭症的患病率为 0.1%（每 10000 人中有 10 人），男女比例为 2:1。自闭症患者中共有 86%存在至少一种共病情况。智力障碍、癫痫、遗尿和注意缺陷多动障碍（ADHD）的患病率分别为 70.3%、29.7%、27%和 21.62%，是自闭症患者最常见的共病情况。母体人格障碍也与自闭症风险增加有关。
本研究表明，伊朗儿童和青少年自闭症及其共病的流行率较高。此外，还发现一些母体精神障碍与自闭症的风险之间存在关系。
