Yaamika Harshini, Muralidas Divya, Elumalai Karthikeyan
Department of Pharmaceutical Chemistry, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamilnadu, India.
J Taibah Univ Med Sci. 2023 Sep 5;18(6):1646-1661. doi: 10.1016/j.jtumed.2023.08.004. eCollection 2023 Dec.
This review examines the immunological and autoimmune adverse events associated with COVID-19 vaccines, highlighting their frequencies, reported cases, and associations with specific vaccine classes. The concept of vaccine-induced immune thrombotic thrombocytopenia is crucial in addressing vaccine skepticism. Understanding this concept helps healthcare professionals identify and manage potential adverse events after vaccination. Despite their rarity, immunological and autoimmune adverse events cause concern and anxiety among the public. To maintain public trust in vaccination programs, healthcare professionals and public health agencies must actively monitor and address these adverse events, promptly disclose suspicious incidents, take measures to mitigate dangers, and inform the public with transparency and accurate information. Continuing research and surveillance are essential for understanding the underlying mechanisms of these adverse events and developing strategies to minimize their occurrence.
本综述探讨了与2019冠状病毒病(COVID-19)疫苗相关的免疫和自身免疫不良事件,重点介绍了其发生频率、报告病例以及与特定疫苗类别的关联。疫苗诱导的免疫性血栓性血小板减少症这一概念对于解决疫苗怀疑论至关重要。理解这一概念有助于医护人员识别和处理接种疫苗后的潜在不良事件。尽管免疫和自身免疫不良事件罕见,但它们引发了公众的担忧和焦虑。为保持公众对疫苗接种计划的信任,医护人员和公共卫生机构必须积极监测和处理这些不良事件,及时披露可疑事件,采取措施减轻危害,并以透明和准确的信息告知公众。持续的研究和监测对于了解这些不良事件的潜在机制以及制定减少其发生的策略至关重要。