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纤维发光聚光器:用于皮肤治疗的闪光灯装置与激光技术之间的桥梁。

Fibered luminescent concentrator: A bridge between flashlamp devices and laser technologies for skin therapy.

作者信息

Le Blanc Catherine, Perrot Jean-Luc, Balembois François

机构信息

Institut d'Optique Graduate School, CNRS, Laboratoire Charles Fabry, Université Paris-Saclay, Palaiseau, France.

Department of Dermatology, University Hospital of Saint Etienne, Saint-Etienne, France.

出版信息

PLoS One. 2024 Dec 18;19(12):e0311425. doi: 10.1371/journal.pone.0311425. eCollection 2024.

DOI:10.1371/journal.pone.0311425
PMID:39693289
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11654970/
Abstract

BACKGROUND AND OBJECTIVES

Laser skin therapy and intense pulsed light (IPL) therapy are both light-based treatments used for various skin concerns. They have been used since decades and each system have their own specificity, advantages, and drawbacks. However specific treatment is still not accessible with standard techniques due to difficulties having a source with both laser and IPL advantages. We describe a new concept, the fibered luminescent concentrator-FLC, based on luminescent concentrators capable of concentrating spectrally and spatially an IPL source, resulting in a multi-color fibered device.

STUDY DESIGN/MATERIALS AND METHODS: The FLC utilizes luminescent materials arranged in parallelepiped shapes polished on all faces. The IPL broadband spectrum is absorbed by the luminescent molecules and is re-emitted to a red shifted wavelength. The emitted spectral bandwidth ranges from green to dark red, depending on the type of luminescent concentrator. This light is then spatially concentrated by total internal reflections in the parallelepiped and guided through a fiber to the final operator.

RESULTS

We have developed three different solid luminescent concentrators based on a transparent polymer sheet (PMMA) doped with luminescent organic dye molecules for yellow and red emission, and an alexandrite crystal for emission in the dark red spectrum. We demonstrate that our new non-laser FLC device can concentrate spectrally and spatially the light with no temporal deformation and offers real opportunities for treatments where the IPL is less well-adapted.

CONCLUSION

The FLC is an additional tool for existing conventional systems such as laser or IPL sources. It is easily adaptable to any IPL source and is a very good complement, especially for wavelengths where the laser cannot easily produce light, such as the yellow band.

摘要

背景与目的

激光皮肤治疗和强脉冲光(IPL)治疗都是用于解决各种皮肤问题的光基治疗方法。它们已经使用了数十年,每种系统都有其自身的特性、优点和缺点。然而,由于难以获得兼具激光和IPL优点的光源,标准技术仍无法实现特定的治疗。我们描述了一种基于发光聚光器的新概念——纤维发光聚光器(FLC),它能够在光谱和空间上对IPL光源进行聚光,从而产生一种多色纤维装置。

研究设计/材料与方法:FLC利用排列成六面体形状且各面都经过抛光的发光材料。IPL宽带光谱被发光分子吸收,并重新发射到红移波长。发射光谱带宽从绿色到深红色不等,这取决于发光聚光器的类型。然后,这种光通过六面体内的全内反射在空间上被聚光,并通过光纤引导至最终的操作人员。

结果

我们基于掺杂了用于黄色和红色发射的发光有机染料分子的透明聚合物片(聚甲基丙烯酸甲酯,PMMA)以及用于深红色光谱发射的变石晶体,开发了三种不同的固体发光聚光器。我们证明,我们新的非激光FLC装置能够在光谱和空间上对光进行聚光,且没有时间变形,为IPL不太适用的治疗提供了真正的机会。

结论

FLC是现有传统系统(如激光或IPL光源)的一种附加工具。它易于适配任何IPL光源,是一种非常好的补充,特别是对于激光难以轻易产生光的波长,如黄色波段。

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本文引用的文献

1
3D luminescent concentrators.
Opt Express. 2021 Mar 1;29(5):6915-6926. doi: 10.1364/OE.415268.
2
The efficacy and safety of a 577-nm high-power optically pumped semiconductor laser in the treatment of postacne erythema.577纳米高功率光泵浦半导体激光治疗痤疮后红斑的疗效与安全性
J Cosmet Dermatol. 2020 Jul;19(7):1642-1647. doi: 10.1111/jocd.13474. Epub 2020 Jun 10.
3
Fiber-Coupled Luminescent Concentrators for Medical Diagnostics, Agriculture, and Telecommunications.光纤耦合荧光集中器在医疗诊断、农业和电信中的应用。
ACS Nano. 2019 Aug 27;13(8):9112-9121. doi: 10.1021/acsnano.9b03335. Epub 2019 Jul 17.
4
Enhancing brightness of Lambertian light sources with luminescent concentrators: the light extraction issue.
Opt Express. 2019 Apr 15;27(8):11830-11843. doi: 10.1364/OE.27.011830.
5
One-year follow-up of a TRASER clinical trial for the treatment of nasal telangiectasias.一项用于治疗鼻毛细血管扩张症的TRASER临床试验的一年随访。
Lasers Surg Med. 2018 Jan;50(1):61-63. doi: 10.1002/lsm.22765. Epub 2017 Nov 24.
6
TRASER: An innovative device for the treatment of nasal telangiectasias.
Lasers Surg Med. 2017 Aug;49(6):625-631. doi: 10.1002/lsm.22651. Epub 2017 Apr 6.
7
Laser and light-based treatments of acne and acne scarring.痤疮及痤疮瘢痕的激光和光基治疗
Clin Dermatol. 2017 Mar-Apr;35(2):183-189. doi: 10.1016/j.clindermatol.2016.10.012. Epub 2016 Oct 27.
8
The role of lasers and intense pulsed light technology in dermatology.激光和强脉冲光技术在皮肤科的作用。
Clin Cosmet Investig Dermatol. 2016 Feb 4;9:29-40. doi: 10.2147/CCID.S69106. eCollection 2016.
9
Future prospects in dermatologic applications of lasers, nanotechnology, and other new technologies.激光、纳米技术及其他新技术在皮肤科应用中的未来前景。
Actas Dermosifiliogr. 2015 Apr;106(3):168-79. doi: 10.1016/j.ad.2014.07.002. Epub 2014 Sep 3.
10
Treatment of refractory melasma with combination of topical 5% magnesium ascorbyl phosphate and fluorescent pulsed light in Asian patients.在亚洲患者中,外用 5%镁抗坏血酸磷酸酯和荧光脉冲光联合治疗难治性黄褐斑。
Int J Dermatol. 2014 Jan;53(1):93-9. doi: 10.1111/ijd.12195. Epub 2013 Oct 29.