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大龄儿童腹股沟疝修补术后复发率高于年幼儿童和成人:一项全国性队列研究。

Older Children Undergoing Inguinal Hernia Repair Have Higher Recurrence Rates Than Younger Children and Adults: A Nationwide Cohort Study.

作者信息

Sincavage John, Sullivan Gwyneth A, Fritsch Annie, Palmisano Zachary, Raval Mehul V, Blakely Martin, Shah Ami N, Gulack Brian C

机构信息

Division of Pediatric Surgery, Rush University Medical Center, Chicago, IL 60622, USA.

Division of Pediatric Surgery, Lurie Children's Hospital, Chicago, IL 60611, USA.

出版信息

J Pediatr Surg. 2025 Mar;60(3):162083. doi: 10.1016/j.jpedsurg.2024.162083. Epub 2024 Dec 3.

Abstract

BACKGROUND

High ligation is the standard practice for inguinal hernia repair in children while adults undergo a floor repair. There is limited data to guide recommendations on the age at which floor repair should be considered. This is a hypothesis-generating study to understand the correlation of age and other factors with inguinal hernia recurrence in children.

MATERIALS AND METHODS

Children aged 6-17 years who underwent inguinal hernia repair by a pediatric surgeon between 2010 and 2022 were identified in the PearlDiver Mariner database, as were adults aged 18-25 years treated by an adult surgeon. Kaplan-Meier survival analysis and Cox proportional hazards modeling was used to determine the risk of hernia recurrence by age, sex, and obesity status.

RESULTS

A total of 15,114 children and 20,863 adults were included. Children aged 16-17 years had a significantly increased five-year risk of hernia recurrence compared to children aged 6-10 years (2.5 % vs 0.8 %, adjusted hazard ratio [AHR]: 3.00, 95 % confidence interval [CI]: 1.98-4.56) as well as compared to the adult group (2.5 % vs 1.2 %, AHR 1.90, 95 % CI: 1.31-2.74). Obese males aged 14-17 years had the highest five-year rate of hernia recurrence of any group at 4.7 %.

CONCLUSIONS

Children 16-17 years of age who underwent inguinal hernia repair with pediatric surgeons have an increased risk of hernia recurrence compared to younger children as well as compared to adults treated by general surgeons. We hypothesize that high ligations, commonly performed by pediatric surgeons, may be inappropriate in some groups of older children.

TYPE OF STUDY

Cohort.

LEVEL OF EVIDENCE

Level III.

摘要

背景

高位结扎术是儿童腹股沟疝修补术的标准术式,而成年人则采用盆底修补术。关于应考虑进行盆底修补术的年龄,可供指导建议的数据有限。这是一项产生假设的研究,旨在了解年龄和其他因素与儿童腹股沟疝复发的相关性。

材料与方法

在PearlDiver Mariner数据库中识别出2010年至2022年间由小儿外科医生进行腹股沟疝修补术的6至17岁儿童,以及由成人外科医生治疗的18至25岁成年人。采用Kaplan-Meier生存分析和Cox比例风险模型,按年龄、性别和肥胖状况确定疝复发风险。

结果

共纳入15114名儿童和20863名成年人。与6至10岁儿童相比,16至17岁儿童的五年疝复发风险显著增加(2.5%对0.8%,调整后风险比[AHR]:3.00,95%置信区间[CI]:1.98 - 4.56),与成人组相比也是如此(2.5%对1.2%,AHR 1.90,95% CI:1.31 - 2.74)。14至17岁的肥胖男性疝复发五年率最高,为4.7%。

结论

与年幼儿童以及普通外科医生治疗的成年人相比,由小儿外科医生进行腹股沟疝修补术的16至17岁儿童疝复发风险增加。我们推测,小儿外科医生通常进行的高位结扎术在某些大龄儿童群体中可能并不合适。

研究类型

队列研究。

证据级别

三级。

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