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一项回顾性队列研究中儿童、青少年及青年成人腹股沟疝修补术的手术方法及结果

Surgical methods and outcomes of inguinal hernia repair in children, adolescents and young adults in a retrospective cohort study.

作者信息

Ma Qiuyue, Liu Xiaoli, Zou Zhenyu, Liang Chen, Chen Jie, Yang Huiqi, Shen Yingmo

机构信息

Department of Hernia and Abdominal Wall Surgery, Beijing Chaoyang Hospital, Capital Medical University, Number 5 Jingyuan Road, Shijingshan District, Beijing, 100043, China.

Department of Hernia and Abdominal Wall Surgery, Peking University People's Hospital, No.11 Xizhimen South Street, Xicheng District, Beijing, 100044, China.

出版信息

Sci Rep. 2025 Mar 17;15(1):9220. doi: 10.1038/s41598-025-93841-5.

Abstract

Laparoscopic repair as an alternative option for pediatric inguinal hernia has increased worldwide. We aimed to analyze the surgical methods of inguinal hernia repair among children, adolescents and young adults, and evaluate the surgical outcomes of reoperation and postoperative complications. This is a hospital-based retrospective cohort study. 3249 inpatients who were ≤ 25 years and underwent inguinal hernia repair between 2015 and 2021 were included. Baseline data, hernia characteristics, surgical approach and technique, outcomes including reoperation and postoperative complications before discharge were identified from electronic medical records. Multivariable Cox regression and logistic regression were used to analyze the association between surgical methods and outcomes. Of all participants, 72.82% were children younger than 9 years, 79.62% were male, 81.19% underwent laparoscopic surgery. Laparoscopic sac high ligation was the mostly used method among infants and children who were younger than 13 years (from 61.11% in 10-12 years old to 96.77% in 0-3 years old), open and laparoscopic tension-free repairs were more common for adolescents and young adults older than 13 years (from 92.38% in 13-15 years old to 100% in 19-21 years old). During a median follow-up of 51.91 months, 24 (0.74%) reoperations were identified, including 3 (0.09%) ipsilateral recurrence, and 21 (0.65%) metachronous contralateral inguinal hernia (MCIH) repair. The rate of complications before discharge was 0.37%. There were no significantly differences in reoperation (aHR = 0.51, 95%CI: 0.12-2.19) and complications (aOR = 0.83, 95%CI: 0.17-4.11) between laparoscopic and open surgery. Age < 3 years (aHR = 6.40, 95%CI: 1.66-24.61), unilateral hernia (aHR = 11.09, 95%CI: 1.46-84.30), and anemia (aHR = 8.58, 95%CI: 1.94-38.05) were independent risk factors for reoperation. Obstruction/gangrene was independent risk factor for complications (aOR = 17.16, 95%CI: 4.07-72.38). Laparoscopic sac high ligation was most commonly performed in children < 13 years, and open and laparoscopic tension-free repairs were more frequently in those > 13 years. Both laparoscopic and open approaches were safe and effective, with low incidence of reoperations and complications.

摘要

腹腔镜修补术作为小儿腹股沟疝的一种替代选择,在全球范围内的应用有所增加。我们旨在分析儿童、青少年和青年成人腹股沟疝修补术的手术方法,并评估再次手术的手术结果和术后并发症。这是一项基于医院的回顾性队列研究。纳入了2015年至2021年间年龄≤25岁且接受腹股沟疝修补术的3249例住院患者。从电子病历中确定基线数据、疝的特征、手术入路和技术,以及包括出院前再次手术和术后并发症在内的结果。采用多变量Cox回归和逻辑回归分析手术方法与结果之间的关联。在所有参与者中,72.82%为9岁以下儿童,79.62%为男性,81.19%接受了腹腔镜手术。腹腔镜疝囊高位结扎术是13岁以下婴幼儿最常用的方法(10 - 12岁为61.11%,0 - 3岁为96.77%),开放式和腹腔镜无张力修补术在13岁以上青少年和青年成人中更为常见(13 - 15岁为92.38%,19 - 21岁为100%)。在中位随访51.91个月期间,确定了24例(0.74%)再次手术,包括3例(0.09%)同侧复发,以及21例(0.65%)异时性对侧腹股沟疝(MCIH)修补。出院前并发症发生率为0.37%。腹腔镜手术和开放手术在再次手术(风险比[HR]=0.51,95%置信区间[CI]:0.12 - 2.19)和并发症(优势比[OR]=0.83,95%CI:0.17 - 4.11)方面无显著差异。年龄<3岁(HR=6.40,95%CI:1.66 - 24.61)、单侧疝(HR=11.09,95%CI:1.46 - 84.30)和贫血(HR=8.58,95%CI:1.94 - 38.05)是再次手术的独立危险因素。梗阻/坏疽是并发症的独立危险因素(OR=17.16,95%CI:4.07 - 72.38)。腹腔镜疝囊高位结扎术最常用于<13岁的儿童,开放式和腹腔镜无张力修补术在>13岁的患者中更常见。腹腔镜和开放手术方法均安全有效,再次手术和并发症发生率低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8420/11914204/c9f7bc357289/41598_2025_93841_Fig1_HTML.jpg

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