Elhfnawy Ahmed, Abdelkhalek Hazem, Elkordy Alaa
Department of Neurology, University of Alexandria, Alexandria, Egypt.
Department of Neurology and Psychiatry, University of Tanta, Tanta, Egypt.
J Neurol Sci. 2025 Jan 15;468:123353. doi: 10.1016/j.jns.2024.123353. Epub 2024 Dec 15.
Subclavian steal syndrome (SSS) is not rarely found during ultrasound examinations. Previous reports demonstrated a relation between ethnic factors and SSS. Data regarding SSS in non-Western population are still lacking. We aimed to investigate the frequency of SSS in a sample of Egyptian population.
In a single-center observational study, we conducted a retrospective analysis of successive patients with competent ultrasound examinations of the brain supplying vessels. The patients presented to our neurovascular laboratory in the context of routine clinical practice.
We enrolled 514 patients in our study. SSS was detected in 9 patients (1.8 %) with a median (IQR) age of 58 (56-63) years. One patient with second-degree SSS received a subclavian stent. Among patients with SSS, 4 patients (44.4 %) had carotid atherosclerosis, 4 patients (44.4 %) had ischemic vascular events in the posterior circulation, and two (22.2 %) had hemodynamically significant carotid stenosis ≥50 %. Using a ROC curve, an interarm SBP (systolic blood pressure) difference of ≥10 mmHg had a sensitivity of 77.8 % and specificity of 66 %, whereas a difference of ≥20 mmHg was associated with a sensitivity of 55.6 % and specificity of 92.4 % for SSS (AUC 0.79, 95 % CI 0.6-0.97, p = 0.004).
SSS is not rare among Egyptian population and should be in mind during ultrasound examination, especially for patient with ischemic events in the posterior circulation and those with significant interarm SBP difference.
锁骨下动脉盗血综合征(SSS)在超声检查中并不罕见。既往报道显示种族因素与SSS之间存在关联。关于非西方人群中SSS的数据仍然缺乏。我们旨在调查埃及人群样本中SSS的发生率。
在一项单中心观察性研究中,我们对连续进行脑供血血管超声检查且结果正常的患者进行了回顾性分析。这些患者是在常规临床实践中到我们的神经血管实验室就诊的。
我们的研究纳入了514例患者。9例患者(1.8%)检测到SSS,中位(四分位间距)年龄为58(56 - 63)岁。1例二度SSS患者接受了锁骨下动脉支架置入术。在SSS患者中,4例(44.4%)有颈动脉粥样硬化,4例(44.4%)在后循环有缺血性血管事件,2例(22.2%)有血流动力学显著的颈动脉狭窄≥50%。使用ROC曲线,双臂收缩压(SBP)差值≥10 mmHg时,SSS的敏感性为77.8%,特异性为66%;而差值≥20 mmHg时,敏感性为55.6%,特异性为92.4%(AUC 0.79,95% CI 0.6 - 0.97,p = 0.004)。
SSS在埃及人群中并不罕见,在超声检查时应予以考虑,尤其是对于后循环有缺血事件的患者以及双臂SBP差值显著的患者。