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在恩桑比亚圣弗朗西斯医院,通过电视辅助胸腔镜活检诊断出的一例患有复发性单侧胸腔积液患者的胸膜类癌:病例报告

Pleural carcinoid diagnosed via video-assisted thoracoscopy biopsies in a patient with recurrent unilateral pleural effusion at St. Francis hospital Nsambya: a case report.

作者信息

Kiweewa Ronald, Mubiru Abdul, Mugisa Didace, Mwebaze Raymond, Basimbe Francis, Bbosa Brian, Nakitende Kevin, Nabulya Rebecca

机构信息

St. Francis Hospital Nsambya, Mother Kevin Post Graduate School, Kampala, Uganda.

RineCynth Advisory Limited, Kampala, Uganda.

出版信息

J Med Case Rep. 2024 Dec 19;18(1):625. doi: 10.1186/s13256-024-04891-8.

Abstract

BACKGROUND

Pulmonary carcinoids are rare neuroendocrine tumors accounting for less than 1% of all lung cancers. They are classified into two subcategories; typical and atypical carcinoids with the latter tending to grow faster. Historically, open thoracotomy was the standard approach for pulmonary resection. However, in the recent years, video-assisted thoracoscopy has gained popularity and become the preferred technique for resectioning pulmonary carcinoids. This report details the diagnosis and management of a pleural carcinoid tumor in a patient with recurrent unilateral pleural effusion.

CASE PRESENTATION

A 77-year-old African male with a history of hypertension and heart failure with reduced ejection presented with a 6-month history of an irritating non-productive cough, occasional productive episodes and exertional dyspnea but no history of hemoptysis, chest pain, orthopnea, evening fevers, or significant weight loss. Despite multiple interventions, including tube drainage and antituberculosis medications, symptoms persisted. A chest X-ray was performed and it revealed a homogeneous opacity on the left, and a computed tomography scan showed mild pleural thickening especially at the bases. Video-assisted thoracoscopy was performed revealing thickened pleural and biopsies confirmed a diagnosis of malignant carcinoid tumor. The patient underwent successful pleurodesis, resulting in significant improvement.

CONCLUSION

This case highlights the pivotal role of video-assisted thoracoscopy in diagnosing and managing rare cases such as pulmonary carcinoids when less invasive methods such as thoracentesis fail.

摘要

背景

肺类癌是罕见的神经内分泌肿瘤,占所有肺癌的比例不到1%。它们分为两个亚类:典型类癌和非典型类癌,后者往往生长更快。历史上,开胸手术是肺切除的标准方法。然而,近年来,电视辅助胸腔镜检查越来越受欢迎,并已成为切除肺类癌的首选技术。本报告详细介绍了一名复发性单侧胸腔积液患者胸膜类癌肿瘤的诊断和治疗。

病例介绍

一名77岁的非洲男性,有高血压和射血分数降低的心力衰竭病史,出现刺激性干咳6个月,偶尔有咳痰发作和劳力性呼吸困难,但无咯血、胸痛、端坐呼吸、夜间发热或明显体重减轻史。尽管进行了多种干预措施,包括胸腔引流和抗结核药物治疗,症状仍持续存在。进行了胸部X线检查,显示左侧有均匀的致密影,计算机断层扫描显示轻度胸膜增厚,尤其是在底部。进行了电视辅助胸腔镜检查,发现胸膜增厚,活检确诊为恶性类癌肿瘤。患者成功接受了胸膜固定术,症状明显改善。

结论

本病例强调了电视辅助胸腔镜检查在诊断和治疗罕见病例(如肺类癌)中的关键作用,当胸腔穿刺等侵入性较小的方法失败时。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2425/11658405/6632f1bb2636/13256_2024_4891_Fig1_HTML.jpg

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