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一例服用藜后发生的急性肾小管间质性肾炎

A case of acute tubulointerstitial nephritis following the use of chenopodium album L.

作者信息

Demiray Alparslan, Yılmaz Tuğba, Demiray Sevil, Akgün Hülya, Koçyiğit İsmail

机构信息

Department of Internal Medicine, Faculty of Medicine, Erciyes University, Kayseri, Turkey.

Department of Nephrology, Faculty of Medicine, Erciyes University, Kayseri, Turkey.

出版信息

Int J Emerg Med. 2024 Dec 18;17(1):189. doi: 10.1186/s12245-024-00790-3.

Abstract

INTRODUCTION

Chenopodium album, commonly known as "lambsquarters," is a plant consumed as food and used in traditional medicine. Its popularity is increasing due to the belief that it has fewer side effects compared to synthetic drugs. However, its use can lead to acute or chronic poisoning. The growing interest in herbal remedies, along with uncontrolled usage and disregard for expert recommendations, contributes to adverse effects.

CASE PRESENTATION

A 68-year-old female patient presented to the emergency department with nausea, vomiting, and flank pain following the use of lambsquarters. Impaired kidney function was detected in the patient. A biopsy performed after Chenopodium album usage led to the diagnosis of tubulointerstitial nephritis (TIN). The patient responded positively to corticosteroid and hemodialysis treatment.

DISCUSSION

Caution is necessary in the use of herbal medicines and traditional treatments. A thorough evaluation of factors such as patients' nutritional status, herbal product usage, medication history, and genetic background is crucial. Chenopodium album can cause tubulointerstitial nephritis, resulting in kidney damage. Similarly, heavy metal poisoning through herbal products can lead to kidney damage. Adopting a multidisciplinary approach in the diagnosis and treatment process can contribute to better patient management.

CONCLUSION

This case presents a rare instance of tubulointerstitial nephritis developed due to the use of herbal products. Physicians should inquire about patients' history of exogenous substance use and conduct a comprehensive assessment, keeping such situations in mind. Conscious use of herbal medicines and traditional treatments can help prevent serious complications like kidney damage.

摘要

引言

藜,俗称“猪毛菜”,是一种可食用的植物,也用于传统医学。由于人们认为它比合成药物副作用更少,其受欢迎程度正在上升。然而,其使用可能导致急性或慢性中毒。对草药疗法的兴趣日益浓厚,加上使用不受控制以及无视专家建议,导致了不良反应。

病例报告

一名68岁女性患者在食用藜后因恶心、呕吐和侧腹痛被送往急诊科。检测发现该患者肾功能受损。食用藜后进行的活检诊断为肾小管间质性肾炎(TIN)。患者对皮质类固醇和血液透析治疗反应良好。

讨论

使用草药和传统疗法时必须谨慎。对患者的营养状况、草药产品使用情况、用药史和遗传背景等因素进行全面评估至关重要。藜可导致肾小管间质性肾炎,从而造成肾脏损害。同样,通过草药产品导致的重金属中毒也会导致肾脏损害。在诊断和治疗过程中采用多学科方法有助于更好地管理患者。

结论

本病例呈现了因使用草药产品而引发肾小管间质性肾炎的罕见情况。医生应询问患者的外源性物质使用史并进行全面评估,牢记此类情况。谨慎使用草药和传统疗法有助于预防像肾脏损害这样的严重并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b589/11654423/a86432f7ef15/12245_2024_790_Fig1_HTML.jpg

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