细菌接种物与抗菌剂活性
Bacterial inoculum and the activity of antimicrobial agents.
作者信息
Fry D E, Garrison R N, Trachtenberg L, Polk H C
出版信息
Surg Gynecol Obstet. 1985 Feb;160(2):105-8.
PMID:3969604
Abstract
Experimental and clinical infections have concentrations of bacteria that are greater than the concentrations used in the laboratory for the determination of in vitro activity. When realistic concentrations are used, the antibiotic activity is reduced. The optimum selection of antibiotics may require a re-examination of the laboratory procedures for the determination of sensitivity data.
摘要
实验性感染和临床感染中的细菌浓度高于实验室用于测定体外活性时所使用的浓度。当使用实际浓度时，抗生素活性会降低。抗生素的最佳选择可能需要重新审视测定敏感性数据的实验室程序。
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