Song Xiaozhen, Zheng Juan, Chen Liyu, Ma Fanghua, Li Changmin, Wang Junjie, Du Lingyao, Tang Hong
Mental Health Center, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, People's Republic of China.
Department of Outpatient, West China Hospital, Sichuan University/West China School of Nursing, Sichuan University, Chengdu, 610041, Sichuan, People's Republic of China.
AIDS Res Ther. 2024 Dec 18;21(1):91. doi: 10.1186/s12981-024-00682-9.
This study assessed the effectiveness of case management compared to that of standard care in improving treatment outcomes for first-time antiretroviral therapy (ART) patients in Liangshan Prefecture, China. First-time ART patients (total n = 828) were divided into the Standard Care Group (SCG, n = 419) and Case Management Group (CMG, n = 409). At week 48, the CMG showed higher retention rates (97.7% vs. 93.6%), better adherence, and more complete virological responses (84.2% vs. 64.0%) compared to the SCG. These findings suggest that case management improves adherence and virological suppression in resource-limited areas, though further research is needed to confirm its broader applicability.
本研究评估了在中国凉山州，病例管理与标准护理相比，在改善首次接受抗逆转录病毒治疗（ART）患者治疗结果方面的有效性。首次接受ART治疗的患者（共828例）被分为标准护理组（SCG，419例）和病例管理组（CMG，409例）。在第48周时，与标准护理组相比，病例管理组显示出更高的留存率（97.7%对93.6%）、更好的依从性以及更完全的病毒学反应（84.2%对64.0%）。这些结果表明，病例管理可改善资源有限地区的依从性和病毒学抑制情况，不过仍需进一步研究以证实其更广泛的适用性。
