Joy Sarah, Sreedevi Aswathy, Bhaskaran Renjitha
Department of Community Medicine, Amrita Institute of Medical Sciences Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.
Department of Biostatistics, Amrita Institute of Medical Sciences Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.
Front Public Health. 2024 Dec 4;12:1448343. doi: 10.3389/fpubh.2024.1448343. eCollection 2024.
Multimorbidity, the coexistence of two or more chronic conditions in an individual, has emerged as a significant public health challenge with profound economic implications, exerting substantial strain on healthcare systems and economies worldwide. This study aimed to estimate the prevalence of non-communicable diseases (NCD) related multimorbidity, catastrophic health expenditure (CHE), and associated factors among adults aged ≥40 years in Ernakulam district.
A community-based cross-sectional study was conducted among 420 individuals aged ≥40 years using population probability sampling. The tools used were the Multimorbidity Assessment Questionnaire for Primary Care (MAQ-PC), the WHO STEPS Questionnaire, and the Patient Health Questionnaire-9 (PHQ-9), which assessed non-communicable diseases, diet, physical activity, smoking, alcohol consumption, and depression. A pretested semi-structured questionnaire collected data on health and household expenditures. Multimorbidity was defined as having two or more self-reported NCDs, and CHE was identified when health costs exceeded 10% of a household's expenditure in the past month. Multivariable logistic regression was performed to find independent predictors of multimorbidity and CHE.
The mean age of participants was 60.02 ± 10 years. The prevalence of NCD multimorbidity was 42.6% (95% CI: 37.9-47.3%). The most common dyad was diabetes and hypertension (24.5, 95% CI: 20.4-28.6%). Higher odds of multimorbidity were observed in those aged ≥60 years (aOR = 3.03, 95% CI: 1.95-4.73), unmarried/widowed/divorced (aOR = 2.15, 95% CI: 1.28-3.63), unemployed (aOR = 1.81, 95% CI: 1.14-2.87), and tobacco users (aOR = 3.72, 95% CI: 1.85-7.48). Approximately 32.4% (95% CI: 25.5-39.3%) of households incurred catastrophic health expenditure (CHE) by treating adults with multimorbidity. Age ≥ 60 (aOR = 2.39, 95% CI: 1.99-5.77) and use of outpatient services (aOR = 4.09, 95% CI: 2.01-8.32) were independently associated with higher odds of CHE. IP services and each additional morbidity add ₹22,082.37 ( = 0.557, < 0.001, 95% CI: ₹17,139.88- ₹27,024.86) and ₹1,278.75 ( = 0.128, = 0.044, 95%CI: ₹35.58-₹2,521.92) to healthcare costs, respectively.
The high prevalence of multimorbidity and associated CHE among individuals over 60 years highlights the urgent need for the National Programme for the Prevention and Control of Non-Communicable Diseases to prioritise multimorbidity and its management, especially above 60 years within this age group.
多种慢性病并存,即个体同时患有两种或更多慢性疾病,已成为一项重大的公共卫生挑战,具有深远的经济影响,给全球医疗系统和经济带来了巨大压力。本研究旨在估计埃纳库勒姆区40岁及以上成年人中与非传染性疾病(NCD)相关的多种慢性病并存情况、灾难性医疗支出(CHE)及其相关因素。
采用人群概率抽样方法,对420名40岁及以上个体进行了一项基于社区的横断面研究。使用的工具包括初级保健多种慢性病评估问卷(MAQ-PC)、世界卫生组织(WHO)的“STEPS”问卷和患者健康问卷-9(PHQ-9),这些问卷评估了非传染性疾病、饮食、身体活动、吸烟、饮酒和抑郁情况。通过一份经过预测试的半结构化问卷收集健康和家庭支出数据。多种慢性病并存定义为自我报告患有两种或更多非传染性疾病,当健康成本超过家庭过去一个月支出的10%时,即确定为发生了灾难性医疗支出。进行多变量逻辑回归分析以找出多种慢性病并存和灾难性医疗支出的独立预测因素。
参与者的平均年龄为60.02±10岁。非传染性疾病多种慢性病并存的患病率为42.6%(95%置信区间:37.9 - 47.3%)。最常见的两种疾病组合是糖尿病和高血压(24.5%,95%置信区间:20.4 - 28.6%)。60岁及以上人群(调整后比值比[aOR]=3.03,95%置信区间:1.95 - 4.73)、未婚/丧偶/离异人群(aOR = 2.15,95%置信区间:1.28 - 3.63)、失业人群(aOR = 1.81,95%置信区间:1.14 - 2.87)以及烟草使用者(aOR = 3.72,95%置信区间:1.85 - 7.48)发生多种慢性病并存的几率更高。约32.4%(需注意此处英文原文可能有误,推测应为32.4%,95%置信区间:25.5 - 39.3%)的家庭因治疗患有多种慢性病的成年人而产生了灾难性医疗支出。年龄≥60岁(aOR = 2.39,95%置信区间:1.99 - 5.77)和使用门诊服务(aOR = 4.09,95%置信区间:2.01 - 8.32)与发生灾难性医疗支出的较高几率独立相关。住院服务和每增加一种疾病分别使医疗费用增加22,082.37卢比(β = 0.557,P < 0.001,95%置信区间:17,139.88 - 27,024.86卢比)和1,278.75卢比(β = 0.128,P = 0.044,95%置信区间:35.58 - 2,521.92卢比)。
60岁以上人群中多种慢性病并存及相关灾难性医疗支出的高患病率凸显了国家非传染性疾病预防和控制计划迫切需要将多种慢性病并存及其管理作为优先事项,尤其是在该年龄组60岁以上人群中。