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细胞外囊泡作为对抗人类威胁的“神奇子弹”。

Extracellular vesicles as the "magic bullet" for fighting threats to humanity.

作者信息

Tamura Takaaki, Yoshioka Yusuke, Ochiya Takahiro

机构信息

Department of Molecular and Cellular Medicine, Institute of Medical Science, Tokyo Medical University, Tokyo 160-0023, Japan.

Department of Urology, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.

出版信息

Extracell Vesicles Circ Nucl Acids. 2021 Sep 18;2(3):224-227. doi: 10.20517/evcna.2021.14. eCollection 2021.

Abstract

Many researchers worldwide are currently trying to develop targeted molecular therapies such as nucleic acid medicines or antibody-drug conjugates for various diseases. Writing in , Kim summarized existing technologies for encapsulating therapeutic molecules into exosomes and introduced some human cell lines which are able to produce safe, effective therapeutic exosomes. Their review article offers the "magic bullet" for fighting threats to humanity such as the current coronavirus pandemic.

摘要

目前,全球许多研究人员都在尝试开发针对各种疾病的靶向分子疗法,如核酸药物或抗体药物偶联物。金在《》杂志上撰文,总结了将治疗性分子封装到外泌体中的现有技术,并介绍了一些能够产生安全、有效的治疗性外泌体的人类细胞系。他们的综述文章为应对当前新冠疫情等对人类的威胁提供了“神奇子弹”。

相似文献

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Extracellular vesicles as the "magic bullet" for fighting threats to humanity.细胞外囊泡作为对抗人类威胁的“神奇子弹”。
Extracell Vesicles Circ Nucl Acids. 2021 Sep 18;2(3):224-227. doi: 10.20517/evcna.2021.14. eCollection 2021.
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本文引用的文献

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Biocompatibility of highly purified bovine milk-derived extracellular vesicles.高纯度牛乳源细胞外囊泡的生物相容性
J Extracell Vesicles. 2018 Feb 21;7(1):1440132. doi: 10.1080/20013078.2018.1440132. eCollection 2018.
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Exosomal formulation of anthocyanidins against multiple cancer types.用于对抗多种癌症类型的花色苷外泌体制剂
Cancer Lett. 2017 May 1;393:94-102. doi: 10.1016/j.canlet.2017.02.004. Epub 2017 Feb 12.
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Tumour exosome integrins determine organotropic metastasis.肿瘤外泌体整合素决定器官特异性转移。
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