Tamura Takaaki, Yoshioka Yusuke, Ochiya Takahiro
Department of Molecular and Cellular Medicine, Institute of Medical Science, Tokyo Medical University, Tokyo 160-0023, Japan.
Department of Urology, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.
Extracell Vesicles Circ Nucl Acids. 2021 Sep 18;2(3):224-227. doi: 10.20517/evcna.2021.14. eCollection 2021.
Many researchers worldwide are currently trying to develop targeted molecular therapies such as nucleic acid medicines or antibody-drug conjugates for various diseases. Writing in , Kim summarized existing technologies for encapsulating therapeutic molecules into exosomes and introduced some human cell lines which are able to produce safe, effective therapeutic exosomes. Their review article offers the "magic bullet" for fighting threats to humanity such as the current coronavirus pandemic.
目前，全球许多研究人员都在尝试开发针对各种疾病的靶向分子疗法，如核酸药物或抗体药物偶联物。金在《》杂志上撰文，总结了将治疗性分子封装到外泌体中的现有技术，并介绍了一些能够产生安全、有效的治疗性外泌体的人类细胞系。他们的综述文章为应对当前新冠疫情等对人类的威胁提供了“神奇子弹”。
