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马达加斯加患有和未患2型糖尿病的女性性功能障碍的患病率及相关危险因素:在马达加斯加塔那那利佛一家大学医院中心开展的一项横断面研究

Prevalence and Risk Factors Associated With Sexual Dysfunction in Malagasy Women With and Without Type 2 Diabetes Mellitus: A Cross-Sectional Study in a University Hospital Center, Antananarivo Madagascar.

作者信息

Raharinavalona Sitraka Angelo, Rakotoarimino Nomenjanahary, Andrianiaina Miora Maëva Arielle, Ralamboson Solofo Andrianarivelo, Andrianasolo Radonirina Lazasoa, Rakotomalala Andrianirina Dave Patrick

机构信息

Cardiovascular Diseases and Internal Medicine Departments Soavinandriana Hospital Center Antananarivo Madagascar.

Endocrinology Department Joseph Raseta Befelatanana University Hospital Center Antananarivo Madagascar.

出版信息

Health Sci Rep. 2024 Dec 17;7(12):e70267. doi: 10.1002/hsr2.70267. eCollection 2024 Dec.

Abstract

BACKGROUND AND AIMS

Female sexual dysfunction (FSD) remains a very little studied subject in Madagascar, despite the resulting alteration of quality of life. Our study aims to determine the prevalence and risk factors for sexual dysfunction in Malagasy women with and without type 2 diabetes (T2DM).

METHODS

This was a descriptive and analytical cross-sectional study, carried out in the Endocrinology department of the Joseph Raseta Befelatanana University Hospital Center over a period of 18 months. FSD was assessed using the Female Sexual Function Index questionnaire in women with and without T2DM.

RESULTS

We retained 122 patients with T2DM and 127 without T2DM. The prevalence of FSD was 47.5% in diabetics and 44.1% in non-diabetics. In patients with T2DM, factors associated with FSD were age [50-59 years] (OR = 2.03 [1.03-4.51]), nephropathy (OR = 2.18 [1.09-3.98]), ischemic stroke ( = 0.0483), ischemic heart disease ( = 0.005), carotid atherosclerosis (OR = 2.64 [1.09-7.85]), obesity (OR = 3.64 [1.22-12.3]), calcium channel blocker use (OR = 4.71 [1.35-21.0]), history of genitourinary infections (OR = 2.06 [1.07-4.28]). In patients without T2DM, they were age [50 - 59 years] (OR = 4.86 [2.16-11.3]), age of first sexual intercourse < 18 years (OR = 2.06 [1.04-4.57]), irregular menstrual cycle (OR = 2.02 [1.00-6.37]), number of gestations ≥ 4 (OR = 1.99 [1.00-5.41]), abortion (OR = 3.15 [1.21-29.1]) and number of children ≥ 4 (OR = 2.17 [1.01-4.81]).

CONCLUSION

FSD was more common in diabetics than non-diabetics. Its early management and associated risk factors are necessary to improve the quality of life of patients.

摘要

背景与目的

尽管女性性功能障碍(FSD)会导致生活质量下降,但在马达加斯加,这仍是一个鲜少被研究的课题。我们的研究旨在确定患有和未患有2型糖尿病(T2DM)的马达加斯加女性性功能障碍的患病率及危险因素。

方法

这是一项描述性和分析性横断面研究,在约瑟夫·拉塞塔·贝费拉塔纳纳大学医院中心内分泌科进行,为期18个月。使用女性性功能指数问卷对患有和未患有T2DM的女性进行FSD评估。

结果

我们纳入了122例T2DM患者和127例非T2DM患者。糖尿病患者中FSD的患病率为47.5%,非糖尿病患者中为44.1%。在T2DM患者中,与FSD相关的因素有年龄[50 - 59岁](OR = 2.03 [1.03 - 4.51])、肾病(OR = 2.18 [1.09 - 3.98])、缺血性中风(= 0.0483)、缺血性心脏病(= 0.005)、颈动脉粥样硬化(OR = 2.64 [1.09 - 7.85])、肥胖(OR = 3.64 [1.22 - 12.3])、使用钙通道阻滞剂(OR = 4.71 [1.35 - 21.0])、泌尿生殖系统感染史(OR = 2.06 [1.07 - 4.28])。在非T2DM患者中,相关因素有年龄[50 - 59岁](OR = 4.86 [2.16 - 11.3])、首次性交年龄<18岁(OR = 2.06 [1.04 - 4.57])、月经周期不规律(OR = 2.02 [1.00 - 6.37])、妊娠次数≥4次(OR = 1.99 [1.00 - 5.41])、流产(OR = 3.15 [1.21 - 29.1])以及子女数≥4个(OR = 2.17 [1.01 - 4.81])。

结论

糖尿病患者中FSD比非糖尿病患者更常见。早期管理及其相关危险因素对于改善患者生活质量很有必要。

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Female Sexual Dysfunction.女性性功能障碍。
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Management of Hypertension with Female Sexual Dysfunction.女性性功能障碍与高血压的管理。
Medicina (Kaunas). 2022 May 5;58(5):637. doi: 10.3390/medicina58050637.

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