Alshehri Khalid M, Althobaiti Raghad A, Alqurashi Athar I, Algethami Nada E, Alswat Khaled A
Medicine and Endocrinology, AlHada Armed Forced Hospital, Taif, Saudi Arabia.
Obstetrics and Gynecology Department, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.
Int J Womens Health. 2022 Mar 17;14:385-394. doi: 10.2147/IJWH.S343065. eCollection 2022.
Women with diabetes mellitus or thyroid disorders are at risk of sexual dysfunction. This study aimed to estimate the prevalence of female sexual dysfunction (FSD) in women with diabetes and/or thyroid disorders and the impact of disease control on the ASEX score.
A cross-sectional study for female patients who had a routine clinic visits was included. The Arizona Sexual Experience Scale (ASEX) was used to evaluate for FSD. Those with a total score of ≥19 or scored ≥5 on any item or ≥4 on three items were considered to have FSD.
A total of 253 female patients with a mean age of 39.1 ± 7.3 years were included. Two-thirds of the participants have no FSD. More than half (57.7%) of the participants had a strong desire for sex, and about 20% of the participants were unsatisfied with their orgasm. Compared to those with no FSD, those with FSD had lower BMI (P = 0.375), more likely to have a master's degree or higher (P = 0.117), diabetes (P = 0.879), hypothyroidism (P = 0.625), diabetes-related microvascular and macrovascular complications (P = 0.049), higher HbA1c, fasting glucose, and TSH (P = 0.731, P = 0.161, and P = 0.561, respectively), lower total cholesterol and LDL (P = 0.368 and P = 0.339, respectively), and exercise more regularly (P = 0.929).
FSD was highly prevalent in our study population. Those with type 1 diabetes had the highest ASEX scores. We showed non-significant negative correlations between total ASEX score and both BMI and TSH, as well as a non-significant positive correlation between total ASEX score and both HbA1c and fasting glucose value.
患有糖尿病或甲状腺疾病的女性存在性功能障碍风险。本研究旨在评估糖尿病和/或甲状腺疾病女性中女性性功能障碍（FSD）的患病率以及疾病控制对ASEX评分的影响。
纳入进行常规门诊就诊的女性患者的横断面研究。采用亚利桑那性体验量表（ASEX）评估FSD。总分≥19分或任何一项得分≥5分或三项得分≥4分者被视为患有FSD。
共纳入253例平均年龄为39.1±7.3岁的女性患者。三分之二的参与者无FSD。超过一半（57.7%）的参与者有强烈的性欲望，约20%的参与者对性高潮不满意。与无FSD者相比，有FSD者BMI较低（P = 0.375），更有可能拥有硕士学位或更高学历（P = 0.117），患有糖尿病（P = 0.879）、甲状腺功能减退症（P = 0.625）、糖尿病相关微血管和大血管并发症（P = 0.049），糖化血红蛋白、空腹血糖和促甲状腺激素水平较高（分别为P = 0.731、P = 0.161和P = 0.561），总胆固醇和低密度脂蛋白较低（分别为P = 0.368和P = 0.339），且运动更规律（P = 0.929）。
FSD在我们的研究人群中非常普遍。1型糖尿病患者的ASEX评分最高。我们发现ASEX总分与BMI和促甲状腺激素之间存在无统计学意义的负相关，以及ASEX总分与糖化血红蛋白和空腹血糖值之间存在无统计学意义的正相关。
