Peritumoral vessel characteristics on magnetic resonance venography reflect the sinus invasion status of para-sinus meningioma.

BACKGROUND

Early recognition of sinus invasion for meningiomas matters the clinical intervention. Therefore, we retrospectively investigated the relationship between peritumoral vessel features on magnetic resonance venography (MRV) and sinus invasion status.

METHODS

Images of phase contrast MRV (PC-MRV, n=46) and contrast-enhanced MRV (CE-MRV, n=39) were independently assessed by four experienced neuroradiologists, including the adjacent sinus status, the peritumoral vessel count and diameter-associated parameters. The sinus invasion status confirmed based on Sindou's criteria during surgery was taken as the gold standard. The relationship between these MRV-based vessel characteristics and sinus invasion status was further analyzed.

RESULTS

The judgment of sinus invasion based on PC-MRV (n=46) and CE-MRV (n=39) revealed a total accuracy of 63% and 74.4%, respectively. The MRV-based vessel count and associated diameter parameters demonstrated statistical differences between the non-invasion and the invasion group (P<0.05). Under the cutoff value of 3 vessels on PC-MRV and 5.5 vessels on CE-MRV, the prediction of sinus invasion status finally achieved the accuracy of 69.6% and 84.6%, respectively. Furthermore, the vessel count, the sum vascular diameter and the max vascular diameter remained significantly different in further subgroup analyses. A comprehensive generalized linear models (GLM) model based on MRV-related vascular features showed the best diagnostic performance on sinus invasion, with the area under the receiver operating characteristic curve of 0.859 for PC-MRV and 0.913 for CE-MRV.

CONCLUSIONS

For para-sinus meningioma, peritumoral vessel characteristics on MRV, especially the vessel count, exhibited close relationships with sinus status, and thus could be a novel tool to predict sinus invasion.