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巴西圣保罗接受暴露前预防以降低艾滋病毒传播风险的跨性别者的社会人口统计学和临床随访概况(2018 - 2021年)

Sociodemographic and clinical follow-up profile of transgender people accessing pre-exposure prophylaxis for the risk of HIV transmission in São Paulo, Brazil (2018-2021).

作者信息

Silva Marcos Morais Santos, Estevam Denize Lotufo, Cardoso Mateus Ettori, Nichiata Lucia Yasuko Izumi

机构信息

Universidade de São Paulo, Escola de Enfermagem, São Paulo, SP, Brazil.

Centro de Referência e Treinamento DST/AIDS-SP, Coordenação Estadual de DST/AIDS de São Paulo, São Paulo, SP, Brazil.

出版信息

Epidemiol Serv Saude. 2024 Dec 16;33(spe1):e2024342. doi: 10.1590/S2237-96222024v33e2024342.especial.en. eCollection 2024.

DOI:10.1590/S2237-96222024v33e2024342.especial.en
PMID:39699388
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11654812/
Abstract

OBJECTIVE

To describe the sociodemographic and clinical follow-up profile of the use of pre-exposure prophylaxis (PrEP) of HIV among transgender people receiving care at a reference health service for sexually transmitted infections and HIV/AIDS in São Paulo, the capital city of São Paulo state, between 2018 and 2021.

METHOD

This was a descriptive study with an analysis of sociodemographic data, reasons for seeking PrEP , discontinuation of use and experiences of clinical follow-up. Descriptive statistics were used.

RESULTS

Among the 53 individuals, the majority were mixed-race (n= 25), transgender women (n= 48), heterosexual (n= 38) and had more than 11 years of study (n= 22). There was a decrease in follow-up visits (n= 14 to n= 3) after the second medical consultation.

CONCLUSION

It is necessary to develop strategies to increase PrEP dispensing and continuation among transgender people, especially among Black people and those with lower level of education.

MAIN RESULTS

The majority of pre-exposure prophylaxis (PrEP) users were young, mixed-race, educated transgender women, reflecting a portion of the transgender population with access to healthcare. The discontinuation of clinical follow-up, especially after the second medical consultation, requires attention.

IMPLICATIONS FOR SERVICES

Individualized strategies should be prioritized to improve the dispensing of PrEP and clinical follow-up for both transgender men and transgender women.

PERSPECTIVES

Further research should focus on investigation of strategies to increase PrEP dispensing and clinical follow-up for transgender people, with an emphasis on transgender men, Black people and those with lower level of education.

摘要

目的

描述2018年至2021年期间,在圣保罗州首府圣保罗市一家性传播感染和艾滋病毒/艾滋病参考健康服务机构接受治疗的跨性别者中,使用艾滋病毒暴露前预防(PrEP)的社会人口统计学和临床随访情况。

方法

这是一项描述性研究,分析社会人口统计学数据、寻求PrEP的原因、停药情况及临床随访经历。采用描述性统计方法。

结果

在53名个体中,大多数为混血(n = 25)、跨性别女性(n = 48)、异性恋(n = 38)且受教育年限超过11年(n = 22)。第二次医疗咨询后随访就诊次数减少(从n = 14降至n = 3)。

结论

有必要制定策略,以增加跨性别者,尤其是黑人和受教育程度较低者的PrEP发放量及持续使用率。

主要结果

大多数艾滋病毒暴露前预防(PrEP)使用者为年轻、混血、受过教育的跨性别女性,这反映了一部分有机会获得医疗保健的跨性别群体情况。临床随访的中断,尤其是在第二次医疗咨询之后,需要引起关注。

对服务的启示

应优先采用个性化策略,以改善跨性别男性和跨性别女性的PrEP发放及临床随访情况。

展望

未来研究应着重调查增加跨性别者PrEP发放量及临床随访的策略,重点关注跨性别男性、黑人和受教育程度较低者。

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本文引用的文献

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Adverse effects of daily oral pre-exposure prophylaxis in men who have sex with men and transgender women: a systematic review and meta-analysis.每日口服暴露前预防措施对男男性行为者和跨性别女性的不良反应:系统评价和荟萃分析。
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Barriers to Pre-Exposure Prophylaxis (PrEP) use for HIV: an integrative review.预防 HIV 感染的暴露前预防(PrEP)使用障碍:综合评价。
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Lancet Reg Health Am. 2023 Feb 6;19:100432. doi: 10.1016/j.lana.2023.100432. eCollection 2023 Mar.
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PrEP user profiles, dynamics of PrEP use and follow-up: a cohort analysis at a Belgian HIV centre (2017-2020).PrEP 用户特征、PrEP 使用和随访的动态:比利时艾滋病毒中心的队列分析(2017-2020 年)。
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Exploring barriers and facilitators to PrEP use among transgender women in two urban areas: implications for messaging and communication.探讨两个城市地区跨性别女性中使用 PrEP 的障碍和促进因素:对信息传递和沟通的启示。
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The worldwide burden of HIV in transgender individuals: An updated systematic review and meta-analysis.全球跨性别者中的 HIV 负担:一项更新的系统评价和荟萃分析。
PLoS One. 2021 Dec 1;16(12):e0260063. doi: 10.1371/journal.pone.0260063. eCollection 2021.
7
Chronic Hepatitis B Infection Among Preexposure Prophylaxis Users Enrolled in a Population-Based Program in British Columbia, Canada.加拿大不列颠哥伦比亚省一项基于人群的项目中接受暴露前预防的人群中的慢性乙型肝炎感染情况。
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