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预防 HIV 感染的暴露前预防（PrEP）使用障碍：综合评价。

Barriers to Pre-Exposure Prophylaxis (PrEP) use for HIV: an integrative review.

机构信息

Universidade de São Paulo. Ribeirão Preto, São Paulo, Brasil.

Escola Superior de Enfermagem de Coimbra. Coimbra, Portugal.

出版信息

Rev Bras Enferm. 2023 Jun 26;76(3):e20210963. doi: 10.1590/0034-7167-2021-0963. eCollection 2023.

DOI:10.1590/0034-7167-2021-0963
PMID:37377313
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10292616/
Abstract

OBJECTIVES

to identify and synthesize scientific evidence on the barriers and difficulties for Pre-exposure Prophylaxis (PrEP) use and compliance for HIV.

METHODS

an integrative literature review, using the MEDLINE/PubMed, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Academic Search Premier and Scopus (Elsevier) databases.

RESULTS

all (100%) the articles included identified that PrEP users experience some type of structural barrier related to health services such as long distance from the units, suboptimal logistics for taking pills and professional resistance to prescribing PrEP. Furthermore, 63.21% identified social barriers, such as stigma about sexuality and HIV, in addition to individual barriers such as alcohol use, adverse effects, and concerns about long-term toxicity.

CONCLUSIONS

the barriers to PrEP use are multifactorial. Effective interventions are needed to support PrEP users in accessing, complying with, and retaining health services.

摘要

目的

识别和综合有关艾滋病毒暴露前预防（PrEP）使用和依从性的障碍和困难的科学证据。

方法

使用 MEDLINE/PubMed、护理与健康相关文献累积索引（CINAHL）、学术搜索高级版和 Scopus（爱思唯尔）数据库进行综合文献回顾。

结果

所有（100%）纳入的文章都指出，PrEP 用户经历了与卫生服务相关的某种结构障碍，例如距离单位较远、服用药物的物流条件不佳以及专业人员抵制开具 PrEP 处方。此外，63.21%的文章还发现了社会障碍，如对性和 HIV 的污名化，以及个体障碍，如饮酒、不良反应和对长期毒性的担忧。

结论

PrEP 使用的障碍是多因素的。需要有效的干预措施来支持 PrEP 用户获得、遵守和保留卫生服务。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94f0/10292616/14878c267a0e/0034-7167-reben-76-03-e20210963-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94f0/10292616/14878c267a0e/0034-7167-reben-76-03-e20210963-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94f0/10292616/14878c267a0e/0034-7167-reben-76-03-e20210963-gf01.jpg

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