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高能量短程房颤消融术:成功与复发的长期预测因素——多变量分析

High Power Short Duration Atrial Fibrillation Ablation: Long-Term Predictors of Success and Recurrence - A Multivariate Analysis.

作者信息

Vassallo Fabricio, Cunha Christiano, Corsino Lucas, Serpa Eduardo, Simões Aloyr, Hespanhol Dalton, Lovatto Carlos Volponi, Gasparini Dalbian, Barbosa Luiz Fernando, Schmidt Andre

机构信息

Hospital Santa Rita de Cássia, Vitória, ES - Brasil.

Escola Superior de Ciências da Santa Casa de Misericórdia de Vitória Faculdade de Medicina - Arritmias Cardíacas, Vitória, ES - Brasil.

出版信息

Arq Bras Cardiol. 2024 Nov;121(12):e20230837. doi: 10.36660/abc.20230837.

DOI:10.36660/abc.20230837
PMID:39699452
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11634315/
Abstract

BACKGROUND

Point-by-point ablation with a high-power short-duration (HPSD) technique in atrial fibrillation (AF) ablation is used worldwide. Little data is available with the HPSD and dragging technique (DT).

OBJECTIVE

To perform a multivariate analysis of clinical and procedural predictors of success and recurrence in HPSD with DT.

METHODS

214 patients in the first AF ablation in sinus rhythm were prospectively enrolled. DT with radiofrequency power of 50 W and contact force (CF) of 10-20 g and 5-10 g at a flow rate of 40 mL/min were applied on the anterior and posterior walls, respectively. Statistical significance was defined as p < 0.05.

RESULTS

143 (66.8%) males, paroxysmal AF (PAF) in 124 (57.9%), with 61.1±12.3 years and followed for 32.8±13.2 months. After 90 days, AF occurred in 43 (20.1%) patients, 19 (15.3%) from PAF, and 24 (26.7%) in persistent AF (PersAF). Multivariate analysis indicated as clinical predictors of recurrence: age ≥ 65 years (p=0.006); obesity [body mass index > 30 (p=0.009)]; CHA2DS2VASC score ≥ 3 (p=0.003); and PersAF (p=0.045). The procedural predictor of recurrence was a heart rate increase < 10% (p=0.006). Predictors of success were an increase in heart rate ≥ 30% (p=0.04) and < 60 min in left atrium time (LAT) (p=0.007).

CONCLUSION

AF ablation with DT and HPSD clinical and procedural predictors of recurrence were ≥ 65 years, obesity, a CHA2DS2VASC ≥ 3, PersAF, and a heart rate increase of < 10% after ablation. Success predictors were an increase of ≥ 30% in heart rate and low LAT (< 60 min).

摘要

背景

心房颤动(AF)消融术中的高功率短持续时间(HPSD)逐点消融技术在全球范围内被广泛应用。关于HPSD和拖曳技术(DT)的数据较少。

目的

对采用DT的HPSD消融成功及复发的临床和手术预测因素进行多变量分析。

方法

前瞻性纳入214例首次进行窦性心律AF消融的患者。分别在前后壁应用射频功率为50W、接触力(CF)在前壁为10 - 20g、后壁为5 - 10g且流速为40mL/min的DT。统计学显著性定义为p < 0.05。

结果

143例(66.8%)为男性,124例(57.9%)为阵发性AF(PAF),年龄61.1±12.3岁,随访32.8±13.2个月。90天后,43例(20.1%)患者发生AF,其中PAF患者19例(15.3%),持续性AF(PersAF)患者24例(26.7%)。多变量分析表明复发的临床预测因素为:年龄≥65岁(p = 0.006);肥胖[体重指数>30(p = 0.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdd6/11634315/fbb0131a128a/0066-782X-abc-121-12-e20230837-gf03-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdd6/11634315/c16c5cd5a9f7/0066-782X-abc-121-12-e20230837-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdd6/11634315/4fd783adb41a/0066-782X-abc-121-12-e20230837-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdd6/11634315/50c0abbf2f31/0066-782X-abc-121-12-e20230837-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdd6/11634315/03862ae48087/0066-782X-abc-121-12-e20230837-gf01-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdd6/11634315/0e88bbac0a2b/0066-782X-abc-121-12-e20230837-gf02-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdd6/11634315/fbb0131a128a/0066-782X-abc-121-12-e20230837-gf03-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdd6/11634315/c16c5cd5a9f7/0066-782X-abc-121-12-e20230837-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdd6/11634315/4fd783adb41a/0066-782X-abc-121-12-e20230837-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdd6/11634315/50c0abbf2f31/0066-782X-abc-121-12-e20230837-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdd6/11634315/03862ae48087/0066-782X-abc-121-12-e20230837-gf01-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdd6/11634315/0e88bbac0a2b/0066-782X-abc-121-12-e20230837-gf02-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdd6/11634315/fbb0131a128a/0066-782X-abc-121-12-e20230837-gf03-en.jpg

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J Cardiovasc Electrophysiol. 2024 May;35(5):975-983. doi: 10.1111/jce.16245. Epub 2024 Mar 14.
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The effect of varying irrigation flow rate during irrigated radiofrequency ablation on optimising lesion shape.在灌溉式射频消融过程中改变灌溉流速对优化病灶形状的影响。
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Progression of Atrial Fibrillation after Cryoablation or Drug Therapy.冷冻消融或药物治疗后心房颤动的进展。
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Cryoablation or Drug Therapy for Initial Treatment of Atrial Fibrillation.冷冻消融或药物治疗用于初始治疗心房颤动。
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