Yang Jianghua, Wu Zhikai, Dai Mingzhou, Xu Changbao, Pan Tiejun, Yin Guangmin, Li Zhuohang, Xu Kewei
Department of Urology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 33 Yingfeng Road, Haizhu District, Guangzhou, 510000, Guangdong, China.
Department of Urology, The Second Affiliated Hospital of Zhengzhou University Zhengzhou, Zhengzhou, 450014, Henan, China.
World J Urol. 2024 Dec 19;43(1):38. doi: 10.1007/s00345-024-05400-8.
The purpose of this study was to assess the feasibility of a pressure-controlled and temperature-controlled flexible ureteroscope system (PT Scope™) during flexible ureteroscopy.
We developed the PT Scope™, a novel ureteroscope system with capabilities for monitoring and controlling intrarenal pressure and temperature to maintain them within set parameters. Data were retrospectively collected from 48 consecutive patients diagnosed with upper urinary tract stones who underwent flexible ureteroscopic lithotripsy using the PT Scope™ across five centers in China. Analyses focused on 24-h postoperative stone-free rates, intrarenal pressure and temperature measurements, and other procedural data.
Among the 48 patients treated with the PT Scope™ system, a significant stone-free rate of 89.6% was achieved within 24 h postoperation, without any instances of intraoperative complications such as perforation or mucosal hemorrhage. Only two patients reported mild postoperative pain and were managed with NSAIDs, and there were no cases of postoperative fever or sepsis. The average maximum intrarenal pressure and temperature were recorded at 30.2 ± 4.20 mmHg and 36.6 ± 4.27 °C, respectively. Notably, during lithotripsy, both the pressure and temperature were maintained below 30 mmHg and 43 °C for 99% of the procedure duration, respectively.
This preliminary investigation indicates that the PT Scope™ is a safe and effective tool for the treatment of upper urinary tract stones, offering the benefit of regulating intrarenal pressure and temperature within predetermined limits. These findings support the feasibility of the system for clinical application.
本研究旨在评估压力控制和温度控制的柔性输尿管镜系统（PT Scope™）在输尿管软镜检查过程中的可行性。
我们开发了PT Scope™，这是一种新型输尿管镜系统，能够监测和控制肾内压力及温度，使其保持在设定参数范围内。回顾性收集了在中国五个中心连续48例被诊断为上尿路结石并使用PT Scope™进行输尿管软镜碎石术的患者的数据。分析重点关注术后24小时无石率、肾内压力和温度测量以及其他手术数据。
在使用PT Scope™系统治疗的48例患者中，术后24小时无石率达到89.6%，未发生任何术中并发症，如穿孔或黏膜出血。只有两名患者报告术后轻度疼痛，使用非甾体抗炎药进行处理，未发生术后发热或脓毒症病例。平均最大肾内压力和温度分别记录为30.2±4.20 mmHg和36.6±4.27°C。值得注意的是，在碎石过程中，压力和温度分别在99%的手术时间内保持在30 mmHg和43°C以下。
这项初步研究表明，PT Scope™是治疗上尿路结石的一种安全有效的工具，具有在预定范围内调节肾内压力和温度的优点。这些发现支持了该系统临床应用的可行性。
