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逆行性肾内手术中下移下极结石是否能提高结石清除率?一项前瞻性随机研究。

Does Relocation of Lower Pole Stone During Retrograde Intrarenal Surgery Improve Stone-Free Rate? A Prospective Randomized Study.

作者信息

Shrestha Anil, Adhikari Baikuntha, Shah Arvind Kumar

机构信息

Department of Urology, National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.

出版信息

J Endourol. 2023 Jan;37(1):21-27. doi: 10.1089/end.2022.0050. Epub 2022 Dec 7.

Abstract

The aim of this study was to compare the stone-free rate (SFR) of treatment relocation and lithotripsy for lower pole stones of less than 2 cm following retrograde intrarenal surgery (RIRS). This prospective randomized study was undertaken from June 2019 to May 2020 in patients undergoing RIRS for lower pole renal stones less than 2 cm in diameter. Patients were randomized into two groups: lithotripsy group and relocation lithotripsy group. The lithotripsy group underwent laser lithotripsy for lower pole stones without relocation of the calculus, and the relocation lithotripsy group had their stones relocated to a favorable location using a tipless Nitinol basket, followed by laser lithotripsy. Laser lithotripsy was achieved using the holmium:YAG (Ho:YAG) laser (120 W) with a 200-μm laser fiber. A Double-J stent was placed in all patients at the end of the procedure. Patient demographics, stone characteristics, operative outcomes, and complications were evaluated. The SFR was determined at 1 month postoperatively with a kidney, ureter, and bladder radiograph (KUB) and ultrasound KUB. Sixty-eight patients were included in the study: group ( = 35) and relocation group ( = 33). The mean stone size and stone density were similar between the groups. The total operative duration, lasing duration, and total energy used were similar between the groups. At the 1-month follow-up, the complete SFR was 85.7% and 91% in the lithotripsy and relocation lithotripsy groups, respectively ( = 0.506). Relocation followed by subsequent laser lithotripsy was associated with similar SFRs as with laser lithotripsy for lower pole renal calculi less than 2 cm in diameter following RIRS using the Ho:YAG laser.

摘要

本研究的目的是比较逆行肾内手术(RIRS)后,治疗直径小于2 cm的下极肾结石时,治疗重新定位与碎石术的无结石率(SFR)。本前瞻性随机研究于2019年6月至2020年5月对直径小于2 cm的下极肾结石接受RIRS的患者进行。患者被随机分为两组:碎石术组和重新定位碎石术组。碎石术组对下极结石进行激光碎石术,结石不重新定位,重新定位碎石术组使用无尖端镍钛诺网篮将结石重新定位到有利位置,然后进行激光碎石术。使用钬:钇铝石榴石(Ho:YAG)激光(120 W)和200μm激光光纤进行激光碎石术。所有患者在手术结束时均放置双J支架。评估患者的人口统计学特征、结石特征、手术结果和并发症。术后1个月通过肾脏、输尿管和膀胱X线平片(KUB)及超声KUB确定SFR。68例患者纳入研究:碎石术组(n = 35)和重新定位组(n = 33)。两组间平均结石大小和结石密度相似。两组间总手术时间、激光照射时间和总能量使用相似。在1个月随访时,碎石术组和重新定位碎石术组的完全无结石率分别为85.7%和91%(P = 0.506)。对于直径小于2 cm的下极肾结石,在RIRS后使用Ho:YAG激光进行激光碎石术时,重新定位后再进行激光碎石术的无结石率与单纯激光碎石术相似。

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