Abdirizak Fatima, Winn Amber K, Parikh Rishika, Scobie Heather M, Lu Xiaoyan, Vega Everardo, Almendares Olivia, Kirking Hannah L, Rose Erica Billig, Silk Benjamin J
Coronavirus and Other Respiratory Viruses Division, National Center for Immunization and Respiratory Diseases, CDC.
MMWR Morb Mortal Wkly Rep. 2024 Dec 19;73(50):1136-1141. doi: 10.15585/mmwr.mm7350a1.
Human adenoviruses (HAdVs) are typically associated with mild respiratory illnesses, although severe disease and outbreaks in congregate settings occur. The National Adenovirus Type Reporting System (NATRS) is a passive, laboratory-based surveillance system that monitors trends in circulation of HAdV types in the United States. This report summarizes the distribution of HAdV types reported to NATRS during 2017-2023. During this 7-year period, 2,241 HAdV specimens with typing results were reported to NATRS. The number of specimens with HAdV typing results reported varied annually during 2017-2019 (range = 389-562) and declined during 2020-2023 (range = 58-356). During 2017-2023, six HAdV types (1-4, 7, and 14) accounted for 88.3% of typed specimens reported; 17.0% of specimens were identified as outbreak-related. An increase in type 41 reporting was associated with a hepatitis cluster during 2021-2022. Reporting to NATRS has declined since the COVID-19 pandemic, despite continued HAdV circulation reported through passive laboratory surveillance to the National Respiratory and Enteric Virus Surveillance System. Enhanced participation in NATRS is needed to improve monitoring of circulating HAdV types.
人腺病毒（HAdVs）通常与轻度呼吸道疾病有关，不过在集体场所也会出现严重疾病和疫情暴发。国家腺病毒分型报告系统（NATRS）是一个基于实验室的被动监测系统，用于监测美国腺病毒各型的传播趋势。本报告总结了2017年至2023年期间向NATRS报告的腺病毒各型分布情况。在这7年期间，共有2241份有分型结果的腺病毒标本被报告给NATRS。2017年至2019年期间，每年报告的有腺病毒分型结果的标本数量有所不同（范围为389 - 562份），而在2020年至2023年期间有所下降（范围为58 - 356份）。在2017年至2023年期间，六种腺病毒型（1 - 4型、7型和14型）占报告的分型标本的88.3%；17.0%的标本被确定与疫情有关。41型报告数量的增加与2021年至2022年期间的一次肝炎聚集性病例有关。自新冠疫情以来，向NATRS的报告有所下降，尽管通过被动实验室监测向国家呼吸道和肠道病毒监测系统报告的腺病毒仍在持续传播。需要加强对NATRS的参与，以改善对传播中的腺病毒各型的监测。
