发育神经影像学将如何助力神经发育障碍或精神疾病的预测？挑战与机遇。
How will developmental neuroimaging contribute to the prediction of neurodevelopmental or psychiatric disorders? Challenges and opportunities.
作者信息
Pérez-Edgar Koraly, Dozier Mary, Saxe Rebecca, MacDuffie Katherine E
机构信息
Department of Psychology, Penn State University, USA.
Department of Psychological & Brain Sciences, University of Delaware, USA.
出版信息
Dev Cogn Neurosci. 2025 Jan;71:101490. doi: 10.1016/j.dcn.2024.101490. Epub 2024 Dec 12.
Successful developmental neuroimaging efforts require interdisciplinary expertise to ground scientific questions in knowledge of human development, modify and create technologies and data processing pipelines suited to the young brain, and ensure research procedures meet the needs and protect the interests of young children and their caregivers. This paper brings together four interdisciplinary perspectives to tackle a set of questions that are central for the field to address as we imagine a future role for developmental neuroimaging in the prediction of neurodevelopmental or psychiatric disorders: 1) How do we generate a strong evidence base for causality and clinical relevance? 2) How do we ensure the integrity of the data and support fair and wide access? 3) How can these technologies be implemented in the clinic? 4) What are the ethical obligations for neuroimaging researchers working with infants and young children?
成功的发育神经影像学研究需要跨学科专业知识，以便将科学问题建立在人类发育知识的基础上，改进并创建适合幼儿大脑的技术和数据处理流程，并确保研究程序满足幼儿及其照顾者的需求并保护他们的利益。本文汇集了四个跨学科观点，以解决一系列问题，这些问题是该领域在设想发育神经影像学在神经发育或精神疾病预测中的未来作用时需要解决的核心问题：1）我们如何为因果关系和临床相关性建立强有力的证据基础？2）我们如何确保数据的完整性并支持公平和广泛的获取？3）这些技术如何在临床中实施？4）从事婴幼儿神经影像学研究的人员有哪些伦理义务？
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