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Atorvastatin in Severity-Stratified Pulmonary Sarcoidosis: A Phase II Randomized Controlled Trial.

作者信息

Fontana Joseph R, Moss Joel, Kim Dong-Yun, Stylianou Mario, Levine Stewart J, Barochia Amisha V, Weir Nargues, Folio Les R, Do Huy Michael, Manganiello Vincent

机构信息

Critical Care Medicine and Pulmonary Branch and.

Office of Biostatistics Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland.

出版信息

Am J Respir Crit Care Med. 2025 Mar;211(3):515-518. doi: 10.1164/rccm.202403-0526RL.

DOI:10.1164/rccm.202403-0526RL
PMID:39701029
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11936144/
Abstract
摘要

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本文引用的文献

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Diagnosis and Detection of Sarcoidosis. An Official American Thoracic Society Clinical Practice Guideline.结节病的诊断与检测：美国胸科学会临床实践指南
Am J Respir Crit Care Med. 2020 Apr 15;201(8):e26-e51. doi: 10.1164/rccm.202002-0251ST.
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Endpoints for clinical trials of sarcoidosis.结节病临床试验的终点指标。
Sarcoidosis Vasc Diffuse Lung Dis. 2012 Oct;29(2):90-8.
3
Steroid-sparing effects of pentoxifylline in pulmonary sarcoidosis.己酮可可碱在肺结节病中的激素节省作用。
Sarcoidosis Vasc Diffuse Lung Dis. 2009 Jul;26(2):121-31.
4
The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease.HMG-CoA还原酶抑制剂阿托伐他汀可促进Th2偏向并逆转中枢神经系统自身免疫性疾病中的麻痹状态。
Nature. 2002 Nov 7;420(6911):78-84. doi: 10.1038/nature01158.
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Statins as a newly recognized type of immunomodulator.他汀类药物作为一种新发现的免疫调节剂。
Nat Med. 2000 Dec;6(12):1399-402. doi: 10.1038/82219.
6
Non invasive evaluation of the inflammatory activity in sarcoidosis with high-resolution computed tomography.利用高分辨率计算机断层扫描对结节病炎症活动进行无创评估。
Sarcoidosis Vasc Diffuse Lung Dis. 1997 Mar;14(1):65-72.
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Surveillance for respiratory hazards in the occupational setting [American Thoracic Society].职业环境中呼吸危害的监测[美国胸科学会]
Am Rev Respir Dis. 1982 Nov;126(5):952-6.
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The measurement of dyspnea. Contents, interobserver agreement, and physiologic correlates of two new clinical indexes.呼吸困难的测量。两种新临床指标的内容、观察者间一致性及生理相关性
Chest. 1984 Jun;85(6):751-8. doi: 10.1378/chest.85.6.751.
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The St George's Respiratory Questionnaire.圣乔治呼吸问卷。
Respir Med. 1991 Sep;85 Suppl B:25-31; discussion 33-7. doi: 10.1016/s0954-6111(06)80166-6.