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基于瑜伽和自然疗法的生活方式干预对高血压患者血脂水平的影响及9个月随访:双臂平行组随机对照试验

Effect of a Yoga and Naturopathy-Based Lifestyle Intervention with 9-Month Follow-Up on Lipid Profile in Patients with Hypertension: A Two-Arm Parallel Group Randomized Controlled Trial.

作者信息

Shetty Prashanth, Janardhana Sujatha Kannarpady, Aruchunan Mooventhan, Subbanna Nandeesh Nanjangud, Jayasingh Jyotsna Kamalet, Prakash Ashwin Vontikoppal

机构信息

Department of Dietetics and Nutrition, SDM College of Naturopathy and Yogic Sciences, Ujire, India.

Department of Natural Therapeutics, SDM College of Naturopathy and Yogic Sciences, Ujire, India.

出版信息

Complement Med Res. 2025;32(1):37-44. doi: 10.1159/000543024. Epub 2024 Dec 19.

DOI:10.1159/000543024
PMID:39701056
Abstract

INTRODUCTION

Hypertension is recognized as a modifiable risk factor for cardiovascular diseases, alongside dyslipidemia. Studies have revealed that between 15 and 31% of individuals have both hypertension and dyslipidemia. However, emerging evidence suggests that natural therapies and yoga can help manage mild increases in blood pressure. This study aimed to evaluate the impact of yogic and naturopathy treatments on lipid profiles in hypertensive patients, thereby contributing to the existing literature.

MATERIALS AND METHODS

A randomized controlled experiment was conducted, involving 262 hypertensive patients randomly assigned to either the study group (SG) or control group (CG). The SG, consisting of 131 individuals, received yoga and naturopathic treatments for 10 days, while the CG (n = 131) did not. The lipid profile was measured at the beginning and end of the 10 days, and they were followed up and reassessed after 9 months.

RESULTS

The study involved a total of 262 individuals, with 111 in the SG and 125 in the CG. After the 10-day intervention period, the SG showed significant reductions in total cholesterol, triglycerides, high-density lipoprotein, low-density lipoprotein, very low-density lipoprotein, apolipoprotein-A (Apo-A), apolipoprotein-B (Apo-B), and lipoprotein-A (Lp-A) (p < 0.001) compared to the CG. Also, the change was observed after 9 months in Apo-A, Apo-B, and Lp-A significantly (p < 0.001).

CONCLUSION

These findings underscore the potential of naturopathic and yogic interventions in improving lipid profiles in hypertensive patients, thereby contributing to the current literature. In conjunction with conventional management, these specific interventions could be considered as a safer form of complementary therapy in the treatment of dyslipidemia among hypertensive patients. Thus, these findings hold promise for the integration of naturopathic and yogic therapies in the standard care of hypertensive patients.

摘要

引言

高血压与血脂异常一样,被认为是心血管疾病的一个可改变的风险因素。研究表明,15%至31%的人同时患有高血压和血脂异常。然而,新出现的证据表明,自然疗法和瑜伽有助于控制轻度血压升高。本研究旨在评估瑜伽和自然疗法对高血压患者血脂谱的影响,从而为现有文献做出贡献。

材料与方法

进行了一项随机对照实验,262名高血压患者被随机分配到研究组(SG)或对照组(CG)。研究组由131人组成,接受了为期10天的瑜伽和自然疗法治疗,而对照组(n = 131)未接受治疗。在10天开始和结束时测量血脂谱,并在9个月后进行随访和重新评估。

结果

该研究共涉及262人,其中研究组111人,对照组125人。在为期10天的干预期后,与对照组相比,研究组的总胆固醇、甘油三酯、高密度脂蛋白、低密度脂蛋白、极低密度脂蛋白、载脂蛋白A(Apo-A)、载脂蛋白B(Apo-B)和脂蛋白A(Lp-A)显著降低(p < 0.001)。此外,在9个月后观察到Apo-A、Apo-B和Lp-A有显著变化(p < 0.001)。

结论

这些发现强调了自然疗法和瑜伽干预在改善高血压患者血脂谱方面的潜力,从而为现有文献做出贡献。与传统治疗相结合,这些特定干预措施可被视为高血压患者血脂异常治疗中一种更安全的辅助治疗形式。因此,这些发现为将自然疗法和瑜伽疗法纳入高血压患者的标准护理提供了希望。

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