回应穆蒂等人于2024年对《与睡眠呼吸暂停相关的短暂颅内压升高（B波）：周期性交替模式被忽视的作用》的评论。

In response to Mutti et al. 2024 commentary on "Transient intracranial pressure elevations (B waves) associated with sleep apnea: the neglected role of cyclic alternating pattern".

作者信息

Riedel Casper Schwartz

机构信息

Department of Neurosurgery, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.

Danish Center for Sleep Medicine, Department of Clinical Neurophysiology, Copenhagen University Hospital, Rigshospitalet, Glostrup, Denmark.

出版信息

Fluids Barriers CNS. 2024 Dec 19;21(1):105. doi: 10.1186/s12987-024-00610-z.

DOI:10.1186/s12987-024-00610-z

PMID:39702226

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11656779/

Abstract

The physiology of transient intracranial pressure (ICP) elevations (B waves), remains incompletely understood and appears to involve multiple mechanisms, including obstructive sleep apnea (OSA). Transient ICP elevations are associated with OSA and cyclic alternating pattern (CAP) metrics, suggesting a complex interplay between sleep fragmentation and ICP dynamics. Additionally, CAP metrics could complement standard OSA assessments, providing deeper insights into transient ICP fluctuations, particularly in conditions like normal-pressure hydrocephalus and idiopathic intracranial hypertension. Future studies should explore CAP-ICP interactions to elucidate their physiological and clinical implications.

摘要

短暂性颅内压（ICP）升高（B波）的生理机制仍未完全明确，似乎涉及多种机制，包括阻塞性睡眠呼吸暂停（OSA）。短暂性ICP升高与OSA和周期性交替模式（CAP）指标相关，这表明睡眠片段化与ICP动态之间存在复杂的相互作用。此外，CAP指标可以补充标准的OSA评估，为短暂性ICP波动提供更深入的见解，特别是在正常压力脑积水和特发性颅内高压等情况下。未来的研究应探索CAP与ICP之间的相互作用，以阐明其生理和临床意义。