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消费者对面向消费者的电视广告中处方药适应症的理解。

Consumer Understanding of Prescription Drug Indications in Direct-to-Consumer Television Advertisements.

作者信息

Sullivan Helen W, Aikin Kathryn J, Johnson Mihaela, Ferriola-Bruckenstein Kate

机构信息

US Food and Drug Administration, 10903 New Hampshire Ave, Silver Spring, MD, 20993, USA.

RTI International, Research Triangle Park, NC, 27709, USA.

出版信息

Ther Innov Regul Sci. 2025 Mar;59(2):278-287. doi: 10.1007/s43441-024-00732-4. Epub 2024 Dec 19.

Abstract

BACKGROUND

Prescription drugs may be indicated to treat more than one medical condition, and companies may promote more than one indication in the same direct-to-consumer (DTC) ad. This study examined how presenting multiple prescription drug indications in one DTC television ad affects consumers' processing of drug information.

METHODS

We conducted two studies with adults diagnosed with diabetes (Study 1, N = 408) or rheumatoid arthritis (Study 2, N = 411). We randomly assigned participants to view one of three television ads: primary indication only (Study 1: diabetic peripheral neuropathy; Study 2: rheumatoid arthritis), primary plus a similar secondary indication (Study 1: fibromyalgia; Study 2: psoriatic arthritis), or primary plus a dissimilar secondary indication (Study 1: generalized anxiety disorder; Study 2: ulcerative colitis).

RESULTS

Remembering and understanding the primary indication was not significantly affected by the presence of a secondary indication (similar or dissimilar). Higher health literacy participants remembered and understood secondary indications.

CONCLUSIONS

Including a second indication in DTC television ads does not appear to have detrimental effects and can increase awareness of the second indication for some participants. Industry and regulators should continue to ensure DTC promotion is truthful and non-misleading, irrespective of the number of indications presented.

摘要

背景

处方药可能被用于治疗多种病症,制药公司可能在同一面向消费者的直接广告(DTC)中推广多种适应症。本研究调查了在一则DTC电视广告中展示多种处方药适应症如何影响消费者对药品信息的处理。

方法

我们对被诊断患有糖尿病(研究1,N = 408)或类风湿性关节炎(研究2,N = 411)的成年人进行了两项研究。我们将参与者随机分配观看三则电视广告中的一则:仅主要适应症(研究1:糖尿病性周围神经病变;研究2:类风湿性关节炎)、主要适应症加一个相似的次要适应症(研究1:纤维肌痛;研究2:银屑病关节炎),或主要适应症加一个不相似的次要适应症(研究1:广泛性焦虑症;研究2:溃疡性结肠炎)。

结果

次要适应症(相似或不相似)的存在对主要适应症的记忆和理解没有显著影响。健康素养较高的参与者记住并理解了次要适应症。

结论

在DTC电视广告中纳入第二个适应症似乎没有不利影响,并且可以提高一些参与者对第二个适应症的认知。行业和监管机构应继续确保DTC推广是真实且不具误导性的,无论展示的适应症数量如何。

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