Pahal Sonu, Pahal Vishvender, Chaudhary Amit
Bioinformatics Program, University of Arkansas for Medical Sciences, University of Arkansas at Little Rock, Little Rock, AR, USA.
J Biosci. 2025;50.
Neuroinformatics, an interdisciplinary field integrating neuroscience and informatics, plays a crucial role in understanding the complexities of the brain and neurological diseases such as Alzheimer's disease (AD). This review explores the applications, databases, and tools used in neuroinformatics, focusing on their role in AD research. Neuroinformatics facilitates data integration, analysis, and modeling, enabling researchers to unravel the underlying mechanisms of AD pathology. Various databases and tools provide access to neuroimaging, and genetic and clinical data, facilitating collaborative research and the development of diagnostic and therapeutic strategies. Neuroinformatics holds promise in advancing our understanding and treatment of AD, offering insights into disease progression, biomarker identification, and personalized medicine approaches.
神经信息学是一个融合神经科学和信息学的跨学科领域，在理解大脑的复杂性以及诸如阿尔茨海默病（AD）等神经疾病方面发挥着关键作用。本综述探讨了神经信息学中使用的应用、数据库和工具，重点关注它们在AD研究中的作用。神经信息学促进数据整合、分析和建模，使研究人员能够揭示AD病理学的潜在机制。各种数据库和工具提供了获取神经影像学、基因和临床数据的途径，促进了合作研究以及诊断和治疗策略的开发。神经信息学在推进我们对AD的理解和治疗方面具有前景，为疾病进展、生物标志物识别和个性化医疗方法提供了见解。
