Zhao Lili, Liu Xinhua, Wang Shuping, Yin Zhicheng, An Tianyue, Zhang Jiayu, Liu Ying
School of Traditional Chinese Medicine, Binzhou Medical University, Yantai, China.
College of Pharmaceutical Science, Shandong University of Traditional Chinese Medicine, Jinan, China.
Front Pharmacol. 2024 Dec 5;15:1438947. doi: 10.3389/fphar.2024.1438947. eCollection 2024.
With the advancement of biotechnology and the human pursuit of a healthy lifestyle, investigations on bioactive peptides (BAPs) have received increasing attention. Compared to proteins, BAPs have lower molecular weights and are more easily digested and absorbed by the human body, exhibiting various physiological functions. For instance, they can inhibit the angiotensin-converting enzyme, lower blood pressure, reduce cholesterol, and possess antioxidant, antimicrobial, and antiviral properties. BAPs are major functional food ingredients primarily derived from animals and plants. The latter are particularly favored due to their wide availability, low cost, and diverse bioactivities. In recent years, the research on plant-derived BAPs produced by microbial fermentation has progressed phenomenally. Consequently, this study provides a systematic overview and offers insights into the prospects of fermentation-synthesized plant-derived BAPs, aiming to provide a reference for their subsequent development and utilization.
随着生物技术的进步以及人类对健康生活方式的追求,对生物活性肽(BAPs)的研究受到了越来越多的关注。与蛋白质相比,BAPs分子量较低,更易被人体消化吸收,并具有多种生理功能。例如,它们可以抑制血管紧张素转换酶、降低血压、降低胆固醇,还具有抗氧化、抗菌和抗病毒特性。BAPs是主要的功能性食品成分,主要来源于动物和植物。由于植物来源广泛、成本低廉且具有多种生物活性,因此尤其受到青睐。近年来,微生物发酵生产植物源BAPs的研究取得了显著进展。因此,本研究对发酵合成的植物源BAPs进行了系统综述,并对其前景进行了展望,旨在为其后续的开发利用提供参考。