Chin Yun Ann, Sumbul Zaheer, Teh Yi Lin, Chng Chiaw Ling
Department of Endocrinology, Singapore General Hospital, Singapore, Singapore.
Department of Nuclear Medicine and Molecular Imaging, Singapore General Hospital, Singapore, Singapore.
Case Rep Endocrinol. 2024 Dec 12;2024:1398125. doi: 10.1155/crie/1398125. eCollection 2024.
We report a case of a 60-year-old lady with metastatic follicular thyroid carcinoma (FTC) who was presented with thyrotoxicosis and heart failure symptoms after total thyroidectomy. Clinical features and investigations led to the diagnosis of functional metastatic FTC with concomitant thyrotoxicosis. Levothyroxine therapy was stopped, and she was treated with propylthiouracil (PTU) followed by serial radioiodine treatments (RAITs) with good control of thyrotoxicosis and metastases. Despite having a very high disease burden with metastatic FTC, she has been able to maintain her functional status thus far, 4.5 years after initial diagnosis.
我们报告一例60岁女性转移性滤泡状甲状腺癌（FTC）患者，该患者在全甲状腺切除术后出现甲状腺毒症和心力衰竭症状。临床特征及检查结果确诊为功能性转移性FTC伴甲状腺毒症。停用左甲状腺素治疗，给予丙硫氧嘧啶（PTU）治疗，随后进行系列放射性碘治疗（RAITs），甲状腺毒症和转移灶得到良好控制。尽管转移性FTC疾病负担极高，但自初次诊断以来4.5年，她至今仍能维持其功能状态。
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