Oliveira Maria Clara, Silva Diego Filipe Bezerra, de Oliveira Andrade Allany, Pita de Melo Daniela, de Sousa Ygor Alexandre Beserra, da Silva Luís Otávio Pereira, de Castro Gomes Daliana Queiroga
State University of Paraíba, R. Baraúnas, 351, Bairro Universitário, Campina Grande, PB, 58429-500, Brazil.
Faculty São Francisco de Cajazeiras, Rodovia PB 393, Bairro Jardim Adalgisa, Cajazeiras, PB, 58900-000, Brazil.
Lasers Med Sci. 2024 Dec 20;39(1):300. doi: 10.1007/s10103-024-04264-z.
The aim of this study was to investigate the scientific evidence regarding the effectiveness of modified-ILIB (intravascular laser irradiation of blood) in the control of systemic conditions and/or oral changes during dental care. This systematic literature review study aimed to answer the question, "Is modified-ILIB an effective adjuvant therapy in the control of systemic conditions and/or oral changes in children and adults during dental treatment?". The protocol for this systematic review was registered in the PROSPERO database under number CRD42023493800. The search was carried out in the PubMed, Web of Science, LILACS, SCOPUS and EMBASE databases on June 10, 2024. Google Scholar was used as a search source for gray literature. Randomized clinical trials were included, without restrictions on language or year of publication. The RoB 2.0 tool was used to assess the risk of bias and GRADE was used to check the quality of the evidence. A total of 750 articles were retrieved and five studies were selected for this review. All studies were in English and were carried out in Brazil. The outcomes were periodontal parameters and glycemic control in patients with periodontitis and type II diabetes, anxiety control in pediatric dentistry, postoperative pain after third molar extraction and improving taste in post-COVID-19 patients. The majority of studies had a low risk of bias, while only one study was considered to have some concerns. The quality of evidence from the studies was considered very low. The current evidence does not overwhelmingly support the effectiveness of modified-ILIB in controlling oral and/or systemic conditions in dentistry.
本研究的目的是调查关于改良型血管内激光照射血液（modified-ILIB）在牙科治疗期间控制全身状况和/或口腔变化有效性的科学证据。这项系统文献综述研究旨在回答“改良型ILIB在儿童和成人牙科治疗期间控制全身状况和/或口腔变化方面是否是一种有效的辅助治疗？”这一问题。该系统综述的方案已在PROSPERO数据库中注册，编号为CRD42023493800。检索于2024年6月10日在PubMed、科学网、拉丁美洲和加勒比卫生科学数据库、Scopus和EMBASE数据库中进行。谷歌学术被用作灰色文献的搜索来源。纳入了随机临床试验，对语言或发表年份没有限制。使用RoB 2.0工具评估偏倚风险，并使用GRADE检查证据质量。共检索到750篇文章，本综述选择了5项研究。所有研究均为英文，且在巴西开展。结局指标包括牙周炎和II型糖尿病患者的牙周参数和血糖控制、儿童牙科中的焦虑控制、第三磨牙拔除术后的疼痛以及新冠后患者味觉的改善。大多数研究的偏倚风险较低，而只有一项研究被认为存在一些问题。研究证据的质量被认为非常低。目前的证据并未压倒性地支持改良型ILIB在牙科治疗中控制口腔和/或全身状况的有效性。
