Shaddock L C, Hamernik R P, Axelsson A
Ann Otol Rhinol Laryngol. 1985 Jan-Feb;94(1 Pt 1):87-92. doi: 10.1177/000348948509400118.
Changes in the vasculature of the chinchilla cochlea were quantitatively assessed 45 days after impulse noise exposure of either 155- or 160-dB peak sound pressure level. The condition of the vessels in the lateral wall and spiral lamina of each cochlea was evaluated in terms of 20 morphological parameters. Multivariate statistical analysis identified the parameters that were significantly affected by the noise exposure. Evaluation of these significant parameters indicated a net reduction in blood flow to the cochlea. All of the noise-exposed cochleas showed vascular changes when compared to controls, and the magnitude of these changes was related to the amount of hair cell loss. The vascular changes are presumed to be permanent.
在以155或160分贝峰值声压级进行脉冲噪声暴露45天后，对灰鼠耳蜗的血管变化进行了定量评估。根据20个形态学参数评估每个耳蜗侧壁和螺旋板中的血管状况。多变量统计分析确定了受噪声暴露显著影响的参数。对这些显著参数的评估表明耳蜗血流量净减少。与对照组相比，所有暴露于噪声的耳蜗均显示出血管变化，且这些变化的程度与毛细胞损失量有关。血管变化被认为是永久性的。
