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噪声暴露对毛丝鼠耳蜗的一些血管影响。

Some vascular effects of noise exposure in the chinchilla cochlea.

作者信息

Vertes D, Axelsson A, Lipscomb D M

出版信息

Arch Otorhinolaryngol. 1979;224(1-2):97-101. doi: 10.1007/BF00455230.

DOI:10.1007/BF00455230
PMID:485955
Abstract

Chinchillas were exposed to pink noise at levels ranging from 110 dB (for 8 h) to 125 dB (for 1/4 h). After a 3-week survival period, the animals were terminated without anesthesia and tissues were prepared using a soft-surface preparation technique [Axelsson et al., Acta Otolaryngol. 80, 362 (1975)]. Cochlear hair cell damage as well as vascular pathology was slight. On occasion, a vessel or vessel segment was obviously atypical, thus allowing noise-exposed animals to be differentiated from their non-noise-exposed controls. More often, however, differences between animals were more discrete and only evident through a computer analysis of the data. The specific effects of these particular noise-exposure parameters on the cochlear blood supply of the chinchilla will be discussed.

摘要

将毛丝鼠暴露于强度范围为110分贝(持续8小时)至125分贝(持续1/4小时)的粉红噪声中。在3周的存活期后,在无麻醉的情况下处死动物,并使用软表面制备技术制备组织[Axelsson等人,《耳鼻咽喉学报》80, 362 (1975)]。耳蜗毛细胞损伤以及血管病变轻微。偶尔,一条血管或血管段明显异常,从而使噪声暴露动物能够与未暴露于噪声的对照动物区分开来。然而,更常见的是,动物之间的差异更为细微,只有通过对数据进行计算机分析才能明显看出。将讨论这些特定噪声暴露参数对毛丝鼠耳蜗血液供应的具体影响。

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