López-Garrigós Maite, Ahumada Miguel, Leiva-Salinas María, Blasco Alvaro, Flores Emilio, Leiva-Salinas Carlos
Clinical Laboratory, Hospital Universitario de San Juan, San Juan de Alicante, Spain.
Department of Biochemistry and Molecular Pathology, Universidad Miguel Hernandez, Elche, Spain.
J Patient Saf. 2025 Apr 1;21(3):138-142. doi: 10.1097/PTS.0000000000001308. Epub 2024 Dec 23.
Hypomagnesemia early diagnosis and consequently early, timely magnesium supplementation is of utmost benefit, but it often goes underdiagnosed. The objective was to show and monitor an intervention to identify hypomagnesemia in patients with arrhythmia.
A cross-sectional study was designed in the laboratory. In primary care patients, the Laboratory Information System would automatically add a serum magnesium test when sample availability is present in any request when a diagnosis of arrhythmia is made. We counted the number of detected patients with hypomagnesemia (serum magnesium <1.7 mg/dL, <0.7 mmol/L), and calculated the cost in reagent of each identified case.
In 430 patients with arrhythmia, serum magnesium was measured, and 41 (9.5%) had hypomagnesemia results. One patient showed severe hypomagnesemia values (<1.2 mg/dL and <0.49 mmol/L). Patients with a deficit were significantly ( P <0.01) older than the total group of patients with normal magnesium values (66.3±13.2 versus 61.6±12.5). Each case represented a cost of 3.15€ in reagent.
The automated computer-based intervention to identify patients with hypomagnesemia was useful and affordable, given the cost per detected case.
早期诊断低镁血症并及时补充镁极为有益，但低镁血症常常未被诊断出来。本研究旨在展示并监测一项用于识别心律失常患者低镁血症的干预措施。
在实验室开展了一项横断面研究。对于基层医疗患者，当做出心律失常诊断且有样本时，实验室信息系统会自动添加血清镁检测项目。我们统计了检测出的低镁血症患者（血清镁<1.7mg/dL，<0.7mmol/L）数量，并计算了每个确诊病例的试剂成本。
对430例心律失常患者进行了血清镁检测，其中41例（9.5%）检测结果为低镁血症。1例患者呈现严重低镁血症值（<1.2mg/dL且<0.49mmol/L）。低镁血症患者的年龄显著高于镁值正常的患者总体（P<0.01）（66.3±13.2岁对61.6±12.5岁）。每个病例的试剂成本为3.15欧元。
鉴于每个检测病例的成本，基于计算机的自动干预措施用于识别低镁血症患者既有用又经济实惠。
