一项关于优化改良超滤对接受体外循环的婴幼儿生理参数影响的随机研究。
A randomized study on the impact of optimized modified ultrafiltration on the physiological parameters of infants and children undergoing a cardiopulmonary bypass.
作者信息
Niu Jianhong, Zhai Guangdi, Zhang Wei, Zhou Juanying, Jiang Shengqi, Ma Jianping, Zheng Aibin
机构信息
Department of Cardiology, Affiliated Changzhou Children's Hospital of Nantong University, Changzhou, 213000, China.
Department of Anesthesiology, Affiliated Changzhou Children's Hospital of Nantong University, Changzhou, 213000, China.
出版信息
J Cardiothorac Surg. 2024 Dec 20;19(1):663. doi: 10.1186/s13019-024-03183-y.
BACKGROUND
The aim of this study is to assess the impact of optimized modified ultrafiltration (OMUF) on the physiological parameters of infants and children undergoing cardiopulmonary bypass (CPB).
METHODS
In this randomized clinical trial, 30 pediatric patients were recruited and allocated into the experimental and control groups, each comprising of 15 patients. The experimental group underwent OMUF prior to the termination of CPB and extubation, while the control group received conventional modified ultrafiltration (MUF).
RESULTS
In the experimental group, post-ultrafiltration levels of Na+, Ca++, hemoglobin (Hb), and hematocrit (HCT) exhibited a statistically significant increase compared to pre-ultrafiltration levels (p < 0.05), whereas no statistically significant differences were observed in the control group.
CONCLUSION
The optimization of conventional MUF led to a significant enhancement in ultrafiltration efficacy, thereby exerting a beneficial impact on improving the physiological parameters of pediatric patients during CPB, surpassing conventional practices.
背景
本研究旨在评估优化改良超滤（OMUF）对接受体外循环（CPB）的婴幼儿生理参数的影响。
方法
在这项随机临床试验中，招募了30名儿科患者并将其分为实验组和对照组，每组15名患者。实验组在CPB结束和拔管前进行OMUF，而对照组接受传统改良超滤（MUF）。
结果
实验组超滤后Na+、Ca++、血红蛋白（Hb）和血细胞比容（HCT）水平与超滤前相比有统计学显著升高（p < 0.05），而对照组未观察到统计学显著差异。
结论
传统MUF的优化导致超滤效果显著增强，从而对改善CPB期间儿科患者的生理参数产生有益影响，优于传统做法。
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