Selimoğlu Şen Hadice, Çetin Yilmaz Süreyya, Tekin Veysi, Kaya Süheyla, Kılıç Tarık, Işık Şehmus
Pulmonology Department, Dicle University Medical Faculty, Diyarbakir, Turkey.
Pulmonology Department, Diyarbakır Selahattin Eyyubi State Hospital, Diyarbakır, Turkey.
Cranio. 2024 Dec 22:1-9. doi: 10.1080/08869634.2024.2441529.
Mean apnea-hypopnea duration (AHD) is the mean duration of apnea-hypopneas experienced during sleep and was found as an indicator of blood oxygenation. The aim of this study was to compare and define the differences in clinical, demographic and polysomnographic characteristics of obstructive sleep apnea (OSA) patients in long and short AHD groups and investigate the relationship between apnea-hypopnea index (AHI), oxygen desaturation index (ODI), and sleepiness.
The cross-sectional analysis included 511 OSA patients who were >18 years and followed up between June 2019 and December 2019 in the Sleep Center of university hospital. The consecutive polysomnography reports and patient data were recorded retrospectively.
Polysomnographic evaluation of different AHD groups showed obvious differences. Although there were no statistically significant differences in the overall AHI values. The Epworth measurements, ODI, time that saturation is below 90%, and N1 and N2 sleep were higher in the long AHD group. On the contrary, sleep efficiency, total sleep time, N3 and REM sleep, average oxygen saturation (AOS), and lowest oxygen saturation (LOS) were lower in the long AHD group.
The findings of this study showed that the AHD is a useful indicator of blood oxygenation and, therefore, tissue oxygenation, independent of the AHI. OSA patients with longer AHD have more vascular complications such as diabetes and hypertension. We suggest that the severity of OSA should be monitored with AHD for preventing potential complications of OSA.
平均呼吸暂停低通气持续时间（AHD）是睡眠期间经历的呼吸暂停低通气的平均持续时间，被发现是血液氧合的一个指标。本研究的目的是比较并确定长AHD组和短AHD组阻塞性睡眠呼吸暂停（OSA）患者在临床、人口统计学和多导睡眠图特征方面的差异，并研究呼吸暂停低通气指数（AHI）、氧饱和度下降指数（ODI）与嗜睡之间的关系。
横断面分析纳入了511例年龄大于18岁、于2019年6月至2019年12月在大学医院睡眠中心接受随访的OSA患者。回顾性记录连续的多导睡眠图报告和患者数据。
不同AHD组的多导睡眠图评估显示出明显差异。尽管总体AHI值没有统计学上的显著差异。长AHD组的爱泼沃斯嗜睡量表测量值、ODI、饱和度低于90%的时间以及N1和N2期睡眠更高。相反，长AHD组的睡眠效率、总睡眠时间、N3和快速眼动睡眠、平均氧饱和度（AOS）和最低氧饱和度（LOS）更低。
本研究结果表明，AHD是血液氧合以及组织氧合的一个有用指标，独立于AHI。AHD较长的OSA患者有更多诸如糖尿病和高血压等血管并发症。我们建议用AHD监测OSA的严重程度以预防OSA的潜在并发症。
