Tarçın Gürkan, Ataş Nurgül, Yaşar Mevra, Şahin Kadriye Cansu, Trabzon Gül, Dündar İsmail, Çiçek Dilek, Balkı Hanife Gül, Manyas Hayrullah, Bitkay Abdurrahman, Celiloğlu Can, Özdemir Dilek Semine, Kılıç Sümeyra, Düzcan Kilimci Duygu, Ata Aysun, Çamtosun Emine, Mengen Eda, Karaoğlan Murat, Yüksel Bilgin, Uçaktürk Seyit Ahmet
Adana City Training and Research Hospital, Clinic of Pediatric Endocrinology, Adana, Türkiye
Gaziantep University Faculty of Medicine, Department of Pediatric Endocrinology, Gaziantep, Türkiye
J Clin Res Pediatr Endocrinol. 2025 May 27;17(2):161-167. doi: 10.4274/jcrpe.galenos.2024.2024-9-9. Epub 2024 Dec 23.
To evaluate the impact of continuous glucose monitoring (CGM) assistance on glycemic control in children with type 1 diabetes (T1D) in earthquake-affected regions, comparing those who benefited from CGM with those who did not. Additionally, the study assessed changes in CGM metrics over nine months of CGM use.
A multicenter, cross-sectional study was conducted across 11 centers in Türkiye. Children with T1D were divided into two groups: those who received CGM support (CGM+) and those who continued with finger-stick glucose monitoring (CGM-). Hemoglobin A1c (HbA1c) levels were measured at four intervals: pre-earthquake, 3-6 months, 6-9 months, and 9-12 months post-earthquake. In the second phase, CGM metrics were analyzed over 90-day intervals in the CGM+ group with at least 85% sensor usage.
A total of 532 children were included. Median HbA1c levels decreased from 9.1% pre-earthquake to 8.8% 3-6 months postearthquake (p=0.027). In the CGM+ group, HbA1c levels significantly decreased from 8.8% to 8.3% (p<0.001), while no significant change was observed in the CGM- group. Of the 412 subjects with access to CGM reports, 105 (25.4%) had less than 85% sensor usage and were excluded. In the remaining 307 patients, there was a significant increase in active sensor time and daily glucose measurements, along with a reduction in hypoglycemia frequency over the 90-day intervals (p<0.001 for all three).
CGM assistance improved glycemic control in children with T1D, even under the challenging conditions following a devastating earthquake. These findings highlight the need for broader access to CGM devices to enhance diabetes management.
评估持续葡萄糖监测（CGM）辅助对地震受灾地区1型糖尿病（T1D）儿童血糖控制的影响，比较受益于CGM的儿童与未受益儿童。此外，该研究评估了CGM使用九个月期间CGM指标的变化。
在土耳其的11个中心进行了一项多中心横断面研究。T1D儿童分为两组：接受CGM支持的儿童（CGM+）和继续采用指尖血糖监测的儿童（CGM-）。在四个时间点测量糖化血红蛋白（HbA1c）水平：地震前、地震后3 - 6个月、6 - 9个月和9 - 12个月。在第二阶段，对传感器使用率至少为85%的CGM+组，每90天分析一次CGM指标。
共纳入532名儿童。HbA1c中位数水平从地震前的9.1%降至地震后3 - 6个月的8.8%（p = 0.027）。在CGM+组中，HbA1c水平从8.8%显著降至8.3%（p < 0.001），而CGM-组未观察到显著变化。在412名能够获取CGM报告的受试者中，105名（25.4%）传感器使用率低于85%，被排除。在其余307名患者中，90天期间主动传感器使用时间和每日血糖测量次数显著增加，低血糖发生频率降低（所有三项p < 0.001）。
即使在毁灭性地震后的挑战性条件下，CGM辅助仍改善了T1D儿童的血糖控制。这些发现凸显了更广泛使用CGM设备以加强糖尿病管理的必要性。
