Luvuno F M, Mtshali Z, Baker L W
Br J Surg. 1985 Feb;72(2):123-7. doi: 10.1002/bjs.1800720218.
Amoebic perforation of bowel, the final and most serious manifestation of transmural amoebic colitis, is due to thrombotic occlusion of vessels supplying the segment of bowel with subsequent infarction and ischaemic necrosis. The ischaemic nature of the necrosis is confirmed by its shape and the demonstration of vascular thrombosis in the resected specimens of perforated amoebic colitis. Specimen angiography confirms the avascular area confined to the macroscopic lesions. Thrombotic occlusion and amoebic invasion of blood vessels have been demonstrated histologically. This new information suggests that amoebic perforation of the bowel is due to vascular compromise.
肠阿米巴穿孔是透壁性阿米巴结肠炎的最终且最严重的表现，它是由于供应肠段的血管发生血栓性闭塞，随后出现梗死和缺血性坏死所致。坏死的缺血性质可通过其形状以及在穿孔性阿米巴结肠炎切除标本中血管血栓形成的表现得以证实。标本血管造影证实无血管区域局限于宏观病变处。组织学已证实血管存在血栓性闭塞和阿米巴侵袭。这一新信息表明肠阿米巴穿孔是由于血管受损所致。
