Alavi Karim A
Division of Colon and Rectal Surgery, Department of Surgery, University of Minnesota, St. Paul, MN 55104, USA.
Clin Colon Rectal Surg. 2007 Feb;20(1):33-7. doi: 10.1055/s-2007-970198.
Amebiasis is an important cause of death from parasitic disease worldwide. The causative organism is Entamoeba histolytica, which has an infective cyst stage and a pathogenic and motile trophozoite stage. The clinical presentation can vary from an asymptomatic carrier state to fulminant colitis and colonic perforation. The majority of patients can be managed medically. However, a small percentage of patients require urgent exploration and resection with an associated high mortality rate. Early recognition and initiation of medical therapy including treatment of asymptomatic carriers are vital to preventing catastrophic outcomes.
阿米巴病是全球寄生虫病致死的重要原因。致病生物是溶组织内阿米巴,它有一个感染性包囊阶段和一个致病且具运动性的滋养体阶段。临床表现从无症状携带状态到暴发性结肠炎和结肠穿孔不等。大多数患者可通过药物治疗。然而,一小部分患者需要紧急探查和切除,且相关死亡率很高。早期识别并启动包括治疗无症状携带者在内的药物治疗对于预防灾难性后果至关重要。