Holland A L, McBurney D H, Moossy J, Reinmuth O M
Brain Lang. 1985 Jan;24(1):36-58. doi: 10.1016/0093-934x(85)90096-3.
This paper is a detailed retrospective history of a patient who began to have difficulty with speaking and comprehension in 1967, and whose neuropathological examination at time of death 12 1/2 years later was consistent with a diagnosis of Pick's disease, complicated by neurofibrillary tangles. It follows the deteriorating course of his language abilities in the context of relatively less-impaired general cognitive abilities, using two sources of information. The first is his own written record of his deteriorating abilities, shown in letters and notes he wrote over this period. The second is through an oral history obtained from the patient's family. The purpose of this report is to illustrate in detail the course of a degenerative condition and to suggest the utility of such descriptional records in increasing understanding of language deterioration in dementia.
本文是对一名患者的详细回顾性病史记录。该患者于1967年开始出现言语和理解困难，12年半后死亡时的神经病理学检查结果符合匹克氏病的诊断，并伴有神经原纤维缠结。本文利用两种信息来源，在相对受损较轻的一般认知能力背景下，追踪了他语言能力的恶化过程。第一个来源是他自己关于能力恶化的书面记录，体现在他在这段时间内所写的信件和笔记中。第二个来源是通过从患者家属那里获得的口述历史。本报告的目的是详细说明一种退行性疾病的病程，并表明此类描述性记录在增进对痴呆症语言衰退理解方面的作用。
