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股骨头缺血性坏死早期逆行钻孔髓芯减压的生物增强术

Biological Augmentation With Retro-Drilling Core Decompression in Early Stage of Femoral Head Avascular Necrosis.

作者信息

Bozkurt Murat, Veizi Enejd, Fırat Neslihan, Şahin Ali

机构信息

Department of Orthopedics and Traumatology, Ankara Acıbadem Hospital, Ankara, Turkey.

Department of Orthopedics and Traumatology, Ankara Bilkent City Hospital, Ankara Yıldırım Beyazıt University, Ankara, Turkey.

出版信息

Arthrosc Tech. 2024 Jun 21;13(11):103093. doi: 10.1016/j.eats.2024.103093. eCollection 2024 Nov.

DOI:10.1016/j.eats.2024.103093
PMID:39711905
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11662889/
Abstract

Osteonecrosis of the femoral head can lead to end-stage osteoarthritis when left untreated. The incidence has been on the rise since the onset of the COVID-19 pandemic. Core decompression of the femoral head is usually the first line of surgical treatment when conservative options fail. Additional biologic support (e.g., bone marrow aspiration concentrates, mesenchymal stem cell derivatives, adipose-derived stromal vascular fraction) has been shown to augment the effects of core decompression alone, but the nature and amount of this additional support is still a topic for debate. This technique describes a surgical approach featuring debridement through retro-drilling, core decompression, and biologic augmentation with stromal vascular fraction and bone marrow aspiration concentrate on the early stages of osteonecrosis of the femoral head.

摘要

股骨头坏死若不治疗可导致终末期骨关节炎。自新冠疫情爆发以来,其发病率一直在上升。当保守治疗无效时,股骨头髓芯减压术通常是外科治疗的首选。额外的生物支持(如骨髓抽吸浓缩物、间充质干细胞衍生物、脂肪来源的基质血管成分)已被证明可增强单纯髓芯减压的效果,但这种额外支持的性质和数量仍是一个有争议的话题。本技术描述了一种手术方法,其特点是在股骨头坏死早期通过逆行钻孔进行清创、髓芯减压,并使用基质血管成分和骨髓抽吸浓缩物进行生物增强。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e72/11662889/e9497c982618/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e72/11662889/6718842d3415/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e72/11662889/3120e9919748/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e72/11662889/e9497c982618/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e72/11662889/6718842d3415/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e72/11662889/3120e9919748/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e72/11662889/e9497c982618/gr3.jpg

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本文引用的文献

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Arthroscopic-Assisted Intraosseous Bioplasty of the Humeral Head for Osteonecrosis.关节镜辅助下肱骨头骨坏死的骨内生物成形术
Arthrosc Tech. 2023 Oct 23;12(11):e2013-e2019. doi: 10.1016/j.eats.2023.07.021. eCollection 2023 Nov.
2
Adipose-derived stromal vascular fraction injection following core decompression and biochemistry artificial bone graft implantation in osteonecrosis of the femoral head.核心减压及生物化学人工骨植入后脂肪源性基质血管成分注射治疗股骨头坏死。
Int Orthop. 2023 Jun;47(6):1481-1486. doi: 10.1007/s00264-023-05792-z. Epub 2023 Mar 29.
3
The Co-Use of Stromal Vascular Fraction and Bone Marrow Concentrate for Tendon Healing.
基质血管成分与骨髓浓缩物联合应用于肌腱愈合。
Curr Stem Cell Res Ther. 2023;18(8):1150-1159. doi: 10.2174/1574888X18666230221141743.
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The painful joint after COVID-19 treatment: A study on joint osteonecrosis following COVID-19-related corticosteroid use.新冠治疗后出现的关节疼痛:一项关于 COVID-19 相关皮质类固醇使用后关节骨坏死的研究。
Jt Dis Relat Surg. 2023;34(1):75-83. doi: 10.52312/jdrs.2023.895. Epub 2022 Dec 27.
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Hip Arthroscopy and Core Decompression for Avascular Necrosis of the Femoral Head Using a Specific Aiming Guide: A Step-by-Step Surgical Technique.使用特定瞄准导向器进行髋关节镜检查及股骨头缺血性坏死的髓芯减压术:分步手术技术
Arthrosc Tech. 2021 Nov 29;10(12):e2775-e2782. doi: 10.1016/j.eats.2021.08.015. eCollection 2021 Dec.
6
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Comparison of cell therapy and other novel adjunctive therapies combined with core decompression for the treatment of osteonecrosis of the femoral head : a systematic review and meta-analysis of 20 studies.细胞疗法与其他新型辅助疗法联合核心减压治疗股骨头坏死的比较:20项研究的系统评价和荟萃分析
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