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改变风险因素以及作为肥胖人体测量指标和参数的体重指数、腰围和腰臀比在中风发生中的作用。

The Role of Modifying Risk Factors as Well as Body Mass Index, Waist Circumference and Hip to Waist Ratio as Anthropometric Indicators and Parameters of Obesity in the Occurence of Stroke.

作者信息

Tiric-Campara Merita, Djozic Edina, Kunic Suljo, Salkic Amra, Amidzic Amel, Skopljak Amira

机构信息

General Hospital "Prim.dr Abdulah Nakas", Sarajevo, Bosnia and Herzegovina.

Sarajevo School of Science and Technology, Medical Faculty, Sarajevo, Bosnia and Herzegovina.

出版信息

Mater Sociomed. 2024;36(2):137-142. doi: 10.5455/msm.2024.36.137-142.

DOI:10.5455/msm.2024.36.137-142
PMID:39712333
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11663001/
Abstract

BACKGROUND

Evaluated values of body mass index (BMI), waist circumeference (WC) and waist-to-hip ratio (WHR) increase the risk of stroke, but the extent to which this is mediated by hypertension, diabetes, lipid status, smoking and alcohol consumption is not fully understood.

OBJECTIVE

The aim of this research is to examine the influence of modifying and non-modifying factors as well as obesity defined through BMI, WC and WHR on the occurrence of stroke.

METHODS

A total of 440 subjects were included in the cohort divided in to two groups. The first group were patients with stroke and another without stroke. We investigate modifable factor for stroke (hypertension (HTA), lipid status, diabetes mellitus (DM), smoking, alcohol consumption, educational status) as well as WHR, BMI and WC as determinants for obesitiy.

RESULTS

The majority of respondents in both groups had a secondary level of education. Smoking and alcohol consumption were slightly more prevalent in the group without stroke, while HTA and DM were slightly more prevalent in the group with stroke, but without a statistically significant difference. The largest number of respodents without stroke had HDL cholesterol values in the range of optimal >1.5, 70.9%, while 35.5% of respodents with stroke had values in the risk range, as well as 32.3% in the high risk range. LDL cholesterol values were on average statistically significantly higher in the group of respodents with stroke - 3.77±1.29 compared to the values in respodents without stroke - 3.20±1.20. The largest WC had patients with a hemorrhagic stroke 96.4 ± 15.5 cm. The average BMI was slightly higher in the group of patients with embolic stroke (28.5 ± 2.8) compared to patients with hemorrhagic stroke (28.4 ± 5.9) and thrombotic stroke (28.1 ± 4, 2). WHR was almost identical in all three types of stroke.

CONCLUSION

There is correlation between modifable risk factor and obesity in stroke occurence.

摘要

背景

体重指数(BMI)、腰围(WC)和腰臀比(WHR)的评估值会增加中风风险,但高血压、糖尿病、血脂状况、吸烟和饮酒对此风险的介导程度尚未完全明确。

目的

本研究旨在探讨可改变和不可改变因素以及通过BMI、WC和WHR定义的肥胖对中风发生的影响。

方法

共有440名受试者纳入该队列并分为两组。第一组为中风患者,另一组为无中风患者。我们调查中风的可改变因素(高血压(HTA)、血脂状况、糖尿病(DM)、吸烟、饮酒、教育程度)以及作为肥胖决定因素的WHR、BMI和WC。

结果

两组中的大多数受访者接受过中等教育。吸烟和饮酒在无中风组中略为普遍,而HTA和DM在中风组中略为普遍,但无统计学显著差异。无中风的受访者中,最大数量的HDL胆固醇值处于最佳范围>1.5,占70.9%,而中风受访者中有35.5%的值处于风险范围,32.3%处于高风险范围。中风受访者组的LDL胆固醇值平均在统计学上显著更高——3.77±1.29,而无中风受访者的值为3.20±1.20。出血性中风患者的WC最大,为96.4±15.5厘米。与出血性中风患者(28.4±5.9)和血栓性中风患者(28.1±4.2)相比,栓塞性中风患者组的平均BMI略高(28.5±2.8)。所有三种类型的中风中WHR几乎相同。

结论

中风发生中可改变的危险因素与肥胖之间存在关联。

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Trajectories of Waist-to-Hip Ratio and Adverse Outcomes in Heart Failure with Mid-Range Ejection Fraction.中等射血分数心力衰竭患者的腰臀比轨迹与不良结局。
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