Sui Junyu, Wu Bei, Zheng Yaguang, Mo Zhiyue, Dong Qianyu, Ðoàn Lan N, Yi Stella S, Qi Xiang
Rory Meyers College of Nursing, New York University, New York, NY 10010, USA.
School of Global Public Health, New York University, New York, NY 10003, USA.
Obes Med. 2025 Jan;53. doi: 10.1016/j.obmed.2024.100573. Epub 2024 Dec 5.
Compare racial/ethnic disparities in the prevalence of non-obese type 2 diabetes (T2D) and the proportion of non-obese individuals among T2D patients.
This cross-sectional study used ICD-9/10 codes to ascertain T2D. Participants were classified as non-obese by BMI (<25 kg/m for normal weight; <23 kg/m for Asian Americans), waist circumference (<102 cm for males, <88 cm for females), and waist-to-hip ratio (<0.9 for males, <0.85 for females). The statistical analysis used marginal standardization of predicted probabilities from multivariable logistic regression to calculate the prevalence.
Among 276,736 participants (mean age 51.7, 61.2% female), non-obese T2D prevalence varied: 6.85% (BMI), 4.17% (waist circumference), 3.63% (waist-to-hip ratio). Asian participants had the highest prevalence of normal-weight T2D (2.70% vs. 1.92% in White, OR 1.44, 95% CI: 1.22-1.69) and non-obese T2D by waist circumference (8.04% vs. 3.36%, OR 2.61, 95% CI: 2.35-2.89). Black participants had the highest prevalence using waist-to-hip ratio (5.37% vs. 2.91%, OR 1.91, 95% CI: 1.80-2.03).
Asian Americans showed higher non-obese T2D prevalence by BMI and waist circumference, while Black adults had higher prevalence by waist-to-hip ratio, suggesting different fat distribution patterns.
比较非肥胖型2型糖尿病（T2D）患病率的种族/民族差异以及T2D患者中非肥胖个体的比例。
这项横断面研究使用ICD - 9/10编码来确定T2D。参与者根据体重指数（正常体重<25kg/m²；亚裔美国人<23kg/m²）、腰围（男性<102cm，女性<88cm）和腰臀比（男性<0.9，女性<0.85）被分类为非肥胖。统计分析使用多变量逻辑回归预测概率的边际标准化来计算患病率。
在276,736名参与者中（平均年龄51.7岁，61.2%为女性），非肥胖T2D患病率各不相同：体重指数法为6.85%，腰围法为4.17%，腰臀比法为3.63%。亚裔参与者正常体重T2D患病率最高（白人中为1.92%，亚裔为2.70%，比值比1.44，95%置信区间：1.22 - 1.69），且按腰围计算的非肥胖T2D患病率最高（分别为8.04%和3.36%，比值比2.61，95%置信区间：2.35 - 2.89）。黑人参与者按腰臀比计算的患病率最高（分别为5.37%和2.91%，比值比1.91，95%置信区间：1.80 - 2.03）。
亚裔美国人按体重指数和腰围计算的非肥胖T2D患病率较高，而黑人成年人按腰臀比计算的患病率较高，这表明脂肪分布模式不同。
