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Cureus. 2024 Nov 21;16(11):e74131. doi: 10.7759/cureus.74131. eCollection 2024 Nov.
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本文引用的文献

1
Guillain-Barre syndrome and link with COVID-19 infection and vaccination: a review of literature.吉兰-巴雷综合征及其与新冠病毒感染和疫苗接种的关联:文献综述
Front Neurol. 2024 Jun 5;15:1396642. doi: 10.3389/fneur.2024.1396642. eCollection 2024.
2
Guillain-Barré Syndrome Induced by Vaccination Against COVID-19: A Systematic Review and Meta-Analysis.新冠疫苗接种诱发吉兰-巴雷综合征:一项系统评价与荟萃分析
Cureus. 2023 Apr 14;15(4):e37578. doi: 10.7759/cureus.37578. eCollection 2023 Apr.
3
Guillain-Barré syndrome associated with COVID-19: A systematic review.与新型冠状病毒肺炎相关的吉兰-巴雷综合征:一项系统评价
Brain Behav Immun Health. 2023 Mar;28:100578. doi: 10.1016/j.bbih.2022.100578. Epub 2023 Jan 17.
4
Electrophysiological assessment in patients with COVID-19-related peripheral neuropathies and myopathies: a systematic review.COVID-19 相关周围神经病和肌病患者的电生理学评估:系统评价。
J Neurophysiol. 2023 Jan 1;129(1):191-198. doi: 10.1152/jn.00386.2022. Epub 2022 Dec 7.
5
Peripheral neuropathies during the COVID-19 pandemic: is there a relation?新冠疫情期间的周围神经病变:存在关联吗?
Immunol Res. 2022 Jun;70(3):408-413. doi: 10.1007/s12026-022-09272-1. Epub 2022 Mar 3.
6
COVID-19 and the peripheral nervous system. A 2-year review from the pandemic to the vaccine era.COVID-19 与周围神经系统。从大流行到疫苗时代的 2 年回顾。
J Peripher Nerv Syst. 2022 Mar;27(1):4-30. doi: 10.1111/jns.12482. Epub 2022 Mar 14.
7
Guillain-​Barré Syndrome Associated with COVID-19 Vaccination.与 COVID-19 疫苗接种相关的格林-巴利综合征。
Emerg Infect Dis. 2021 Dec;27(12):3175-3178. doi: 10.3201/eid2712.211634. Epub 2021 Oct 14.
8
COVID-19 vaccine causing Guillain-Barre syndrome, a rare potential side effect.新冠疫苗会引发吉兰-巴雷综合征,这是一种罕见的潜在副作用。
Clin Case Rep. 2021 Aug 30;9(9):e04756. doi: 10.1002/ccr3.4756. eCollection 2021 Sep.
9
COVID-19 mRNA vaccination leading to CNS inflammation: a case series.COVID-19 mRNA 疫苗接种导致中枢神经系统炎症:病例系列研究。
J Neurol. 2022 Mar;269(3):1093-1106. doi: 10.1007/s00415-021-10780-7. Epub 2021 Sep 4.
10
Demyelination as a result of an immune response in patients with COVID-19.COVID-19 患者因免疫反应导致的脱髓鞘。
Acta Neurol Belg. 2021 Aug;121(4):859-866. doi: 10.1007/s13760-021-01691-5. Epub 2021 May 2.

COVID-19大流行之前及期间的外周免疫介导性神经病:在一家转诊中心进行的回顾性横断面研究

Peripheral Immune-Mediated Neuropathy Before and During the COVID-19 Pandemic: A Retrospective Cross-Sectional Study in a Referral Center.

作者信息

Su Michael Angelo O, Doquenia Maria Leila M, Tanglao Michelle J, Rosales Raymond

机构信息

Department of Internal Medicine, Metropolitan Medical Center, Manila, PHL.

Center for Neurodiagnostic and Therapeutic Services, Metropolitan Medical Center, Manila, PHL.

出版信息

Cureus. 2024 Nov 21;16(11):e74131. doi: 10.7759/cureus.74131. eCollection 2024 Nov.

DOI:10.7759/cureus.74131
PMID:39712713
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11662227/
Abstract

BACKGROUND

There are currently seven coronaviruses that can infect humans and the latest addition to these viruses is the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Infection by SARS-CoV-2 is known commonly as coronavirus disease 2019 (COVID-19). Aside from common manifestations of cough and fever, neurologic symptoms such as headache, disturbed consciousness, paresthesia, and seizures have also been seen. By identifying the incidence of peripheral immune-mediated neuropathies (PIMN), early prevention can be made.

METHODS

This cross-sectional retrospective analytic study reviewed the case records of patients examined at the Center for Neurodiagnostic and Therapeutic Services (CNS) of Metropolitan Medical Center from January 2018 to December 2021.

RESULTS

The period incidence of Guillain-Barré Syndrome (GBS) for the years 2018-2019 and 2020-2021 were 9.21% and 24.44%, respectively. The obtained p-value was 0.0226, which was lower than the set p-value of 0.05. Therefore, the period incidence of GBS for 2020-2021 was significantly higher when compared to that of 2018-2019.

CONCLUSION

There has been an increase in cases of GBS during the COVID-19 pandemic.

摘要

背景

目前有七种冠状病毒可感染人类,其中最新出现的是严重急性呼吸综合征冠状病毒2(SARS-CoV-2)。SARS-CoV-2感染通常被称为2019冠状病毒病(COVID-19)。除了咳嗽和发热等常见表现外,还出现了头痛、意识障碍、感觉异常和癫痫发作等神经症状。通过确定外周免疫介导性神经病(PIMN)的发病率,可以进行早期预防。

方法

这项横断面回顾性分析研究回顾了2018年1月至2021年12月在大都会医疗中心神经诊断与治疗服务中心(CNS)接受检查的患者的病例记录。

结果

2018 - 2019年和2020 - 2021年吉兰 - 巴雷综合征(GBS)的期间发病率分别为9.21%和24.44%。得到的p值为0.0226,低于设定的p值0.05。因此,与2018 - 2019年相比,2020 - 2021年GBS的期间发病率显著更高。

结论

在COVID - 19大流行期间,GBS病例有所增加。