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斯内登综合征的全面见解:临床视角

Comprehensive insights of Sneddon syndrome: A clinical perspective.

作者信息

Alazzam Ahmad Yousef

机构信息

Faculty of Medicine, The Hashemite University, Zarqa, Jordan.

出版信息

J Cent Nerv Syst Dis. 2024 Dec 19;16:11795735241308767. doi: 10.1177/11795735241308767. eCollection 2024.

DOI:10.1177/11795735241308767
PMID:39712946
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11660069/
Abstract

BACKGROUND

Sneddon's syndrome is a rare thrombotic vasculopathy characterized by the coexistence of both cerebrovascular events and livedo reticularis.

OBJECTIVE

This review aims to raise awareness among physicians by discussing the whole clinical spectrum of the disease. Typically, Sneddon syndrome presents in middle-aged women with a cerebrovascular accident and a preexisting skin rash, which is livedo reticularis. Diagnosis is primarily clinical, relying on a high index of suspicion. Management focuses mainly on reducing the risk of cerebral infarctions and alleviating symptoms.

CONCLUSION

Further research is necessary to better understand the disease's nature, which will contribute to improving early diagnosis and optimal management.

摘要

背景

斯内登综合征是一种罕见的血栓性血管病,其特征为脑血管事件和网状青斑同时存在。

目的

本综述旨在通过讨论该疾病的整个临床谱,提高医生的认识。通常,斯内登综合征表现为中年女性发生脑血管意外并有既往皮疹,即网状青斑。诊断主要依靠临床,高度怀疑是关键。治疗主要侧重于降低脑梗死风险和缓解症状。

结论

有必要进一步研究以更好地了解该疾病的本质,这将有助于改善早期诊断和优化治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfb8/11660069/6d52f9b4b80c/10.1177_11795735241308767-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfb8/11660069/6d52f9b4b80c/10.1177_11795735241308767-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfb8/11660069/6d52f9b4b80c/10.1177_11795735241308767-fig1.jpg

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本文引用的文献

1
Combination therapy for Sneddon syndrome to reduce the incidence of cerebrovascular complications.联合治疗 Sneddon 综合征以降低脑血管并发症的发生率。
J Dtsch Dermatol Ges. 2024 Jul;22(7):947-954. doi: 10.1111/ddg.15422. Epub 2024 Jun 21.
2
Sneddon Syndrome: A Case Report From Saudi Arabia.斯内登综合征:来自沙特阿拉伯的一例病例报告。
Cureus. 2024 Mar 4;16(3):e55509. doi: 10.7759/cureus.55509. eCollection 2024 Mar.
3
Sneddon's syndrome concurrent with cerebral venous sinus thrombosis: A case report.斯内登综合征并发脑静脉窦血栓形成:一例报告。
World J Clin Cases. 2023 Nov 6;11(31):7656-7662. doi: 10.12998/wjcc.v11.i31.7656.
4
Cognitive and psychiatric signs revealing Sneddon syndrome: A case report.揭示斯内登综合征的认知和精神症状:一例报告。
Clin Case Rep. 2023 Oct 4;11(10):e8013. doi: 10.1002/ccr3.8013. eCollection 2023 Oct.
5
An unusual case of intracerebral hemorrhage: exploring the link with Sneddon's syndrome.一例罕见的脑出血病例:探寻其与斯内登综合征的关联。
Med Klin Intensivmed Notfmed. 2024 Feb;119(1):66-68. doi: 10.1007/s00063-023-01059-y. Epub 2023 Sep 13.
6
Obstructive valve thrombosis after transcatheter aortic valve replacement (TAVR) in Sneddon syndrome without antiphospholipid antibodies.Sneddon 综合征患者行经导管主动脉瓣置换术(TAVR)后发生瓣叶阻塞性血栓,且无抗磷脂抗体。
BMJ Case Rep. 2023 Jun 12;16(6):e254309. doi: 10.1136/bcr-2022-254309.
7
Risk Factors and Causes of Ischemic Stroke in 1322 Young Adults.1322 例青年缺血性脑卒中的危险因素及病因。
Stroke. 2023 Feb;54(2):439-447. doi: 10.1161/STROKEAHA.122.040524. Epub 2022 Dec 13.
8
Anticoagulant Therapy in Patients with Antiphospholipid Syndrome.抗磷脂综合征患者的抗凝治疗
J Clin Med. 2022 Nov 26;11(23):6984. doi: 10.3390/jcm11236984.
9
The diagnostic value of skin biopsies in Sneddon syndrome.皮肤活检在斯内登综合征中的诊断价值。
PLoS One. 2021 Jun 28;16(6):e0253365. doi: 10.1371/journal.pone.0253365. eCollection 2021.
10
Sneddon syndrome: a comprehensive clinical review of 53 patients.斯奈德综合征:53 例患者的综合临床回顾。
J Neurol. 2021 Jul;268(7):2450-2457. doi: 10.1007/s00415-021-10407-x. Epub 2021 Jan 29.