See Aaron Yee Shuen, Kasiviswanathan Pulkit, Syed Masood Pasha, Minervini Marta, Sahin Ibrahim Halil, Krauze Michal
Medical School University of Western Australia Perth Western Australia Australia.
Hamdard Institute of Medical Sciences and Research New Delhi India.
JGH Open. 2024 Dec 20;8(12):e70079. doi: 10.1002/jgh3.70079. eCollection 2024 Dec.
Cardiac metastases are a rare site for metastatic hepatocellular carcinoma (HCC). We describe an atypical presentation of an isolated right ventricular metastasis of HCC following successful treatment with no evidence of primary disease recurrence. The case presented as gradually worsening hypertension and erythrocytosis in the setting of normal surveillance scans and alpha-fetoprotein levels. The mass was detected on transthoracic echocardiogram and treated with surgical resection. Histopathological features of the tumor demonstrated features associated with WNT/β-catenin mutated HCC, such as microtrabecular, acinar, and bile staining with positive glutamine synthetase expression.
心脏转移是转移性肝细胞癌（HCC）的罕见转移部位。我们描述了一例孤立性右心室HCC转移的非典型表现，患者在成功治疗后无原发性疾病复发迹象。该病例表现为在监测扫描和甲胎蛋白水平正常的情况下，高血压和红细胞增多症逐渐加重。经胸超声心动图检测到肿块并进行了手术切除。肿瘤的组织病理学特征显示出与WNT/β-连环蛋白突变型HCC相关的特征，如微小梁、腺泡状以及谷氨酰胺合成酶表达阳性的胆汁染色。
