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择期普通外科和血管外科手术后的衰弱与长期医疗保健利用情况。

Frailty and Long-Term Health Care Utilization After Elective General and Vascular Surgery.

作者信息

Dossabhoy Shernaz S, Graham Laura A, Kashikar Aditi, George Elizabeth L, Seib Carolyn D, Tamura Manjula Kurella, Wagner Todd H, Hawn Mary T, Arya Shipra

机构信息

Department of Surgery, Stanford University School of Medicine, Stanford, California.

Veterans Affairs Palo Alto Health Care System, Palo Alto, California.

出版信息

JAMA Surg. 2025 Feb 1;160(2):210-218. doi: 10.1001/jamasurg.2024.5711.

DOI:10.1001/jamasurg.2024.5711
PMID:39714891
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11822548/
Abstract

IMPORTANCE

Surgical quality improvement efforts have largely focused on 30-day outcomes, such as readmissions and complications. Surgery may have a sustained impact on the health and quality of life of patients considered frail, yet data are lacking on the long-term health care utilization of patients with frailty following surgery.

OBJECTIVE

To examine the independent association of preoperative frailty on long-term health care utilization (up to 24 months) following surgery.

DESIGN, SETTING, AND PARTICIPANTS: This retrospective, observational cohort study included patients undergoing elective general and vascular surgery performed in the Veterans Affairs (VA) Surgical Quality Improvement Program with study entry from October 1, 2013, to September 30, 2018. Patients were followed up for 24 months. Patients with nursing home visits prior to surgery, emergent cases, and in-hospital deaths were excluded. Data analysis was conducted from September 2022 to May 2024.

EXPOSURES

Preoperative frailty as assessed by the Risk Analysis Index (RAI-A) score: robust, less than 20; normal, 20 to 29; frail, 30 to 39; and very frail, 40 or more.

MAIN OUTCOMES AND MEASURES

The primary outcome was health care utilization through 24 months, defined as inpatient admissions, outpatient visits, emergency department (ED) visits, and nursing home or rehabilitation services collected via Corporate Data Warehouse and Centers for Medicare & Medicaid Services data. χ2 Tests and analysis of variance were used to assess preoperative frailty status, and a Cox proportional hazards model was used to calculate the adjusted association of preoperative frailty on each postdischarge health care utilization outcome.

RESULTS

This study identified 183 343 elective general (80.5%) and vascular (19.5%) procedures (mean [SD] age, 62 [12.7] years; 12 915 females [7.0%]; 28 671 Black patients [16.0]; 138 323 White patients [77.3%]; 94 451 Medicare enrollees [51.5%]) with mean (SD) RAI-A score of 22.2 (7.0). After adjustment for baseline characteristics and preoperative use of health care services, frailty was associated with higher inpatient admissions (frail: hazard ratio [HR], 1.75; 95% CI, 1.70-1.79; very frail: HR, 2.33; 95% CI, 2.25-2.42), ED visits (frail: HR, 1.39; 95% CI, 1.36-1.41; very frail: HR, 1.70; 95% CI, 1.65-1.75), and nursing home or rehabilitation encounters (frail: HR, 4.97; 95% CI, 4.36-5.67; very frail: HR, 7.44; 95% CI, 6.34-8.73). For patients considered frail and very frail, health care utilization was higher after surgery and remained significant through 24 months for all outcomes (using piecewise Cox proportional hazards modeling).

CONCLUSIONS AND RELEVANCE

In this study, frailty was a significant risk factor for high long-term health care utilization after surgery. This may have quality of life implications for patients and policy implications for health care systems and payers.

摘要

重要性

外科手术质量改进工作主要集中在30天的结果上,如再入院率和并发症。手术可能会对体弱患者的健康和生活质量产生持续影响,但缺乏关于体弱患者术后长期医疗保健利用情况的数据。

目的

研究术前体弱与术后长期医疗保健利用(长达24个月)之间的独立关联。

设计、设置和参与者:这项回顾性观察性队列研究纳入了在退伍军人事务部(VA)外科质量改进计划中接受择期普通外科和血管外科手术的患者,研究入组时间为2013年10月1日至2018年9月30日。对患者进行了24个月的随访。排除术前有养老院就诊记录、急诊病例和院内死亡的患者。数据分析于2022年9月至2024年5月进行。

暴露因素

通过风险分析指数(RAI-A)评分评估的术前体弱情况:强健,低于20分;正常,20至29分;体弱,30至39分;非常体弱,40分及以上。

主要结局和衡量指标

主要结局是24个月内的医疗保健利用情况,定义为通过企业数据仓库和医疗保险与医疗补助服务中心数据收集的住院入院、门诊就诊、急诊室(ED)就诊以及养老院或康复服务。使用卡方检验和方差分析评估术前体弱状态,并使用Cox比例风险模型计算术前体弱与每个出院后医疗保健利用结局之间的调整关联。

结果

本研究确定了183343例择期普通外科(80.5%)和血管外科(19.5%)手术(平均[标准差]年龄,62[12.7]岁;12915名女性[7.0%];28671名黑人患者[16.0%];138323名白人患者[77.3%];94451名医疗保险参保者[51.5%]),平均(标准差)RAI-A评分为22.2(7.0)。在对基线特征和术前医疗保健服务使用情况进行调整后,体弱与更高的住院入院率(体弱:风险比[HR],1.75;95%置信区间,1.70-1.79;非常体弱:HR,2.33;95%置信区间,2.25-2.42)、急诊室就诊率(体弱:HR,1.39;95%置信区间,1.36-1.41;非常体弱:HR,1.70;95%置信区间,1.65-1.75)以及养老院或康复服务接触率(体弱:HR,4.97;95%置信区间,4.36-5.67;非常体弱:HR,7.44;95%置信区间,6.34-8.73)相关。对于被认为体弱和非常体弱的患者,术后医疗保健利用更高,并且在所有结局方面直至24个月时仍具有显著性(使用分段Cox比例风险模型)。

结论和相关性

在本研究中,体弱是术后长期医疗保健高利用率的一个重要风险因素。这可能对患者的生活质量产生影响,并对医疗保健系统和支付方具有政策意义。

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Association of Frailty with Healthcare Utilization for Patients over One Year Following Surgical Evaluation.手术评估后一年以上患者的虚弱与医疗保健利用的关联
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