Golastani Bahar, Poursafa Parinaz, Zarean Maryam, Yazdi Maryam, Heidari-Beni Motahar, Kelishadi Roya
Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.
Faculty of Social Sciences, Tampere University, Tampere, Finland.
Adv Biomed Res. 2024 Oct 28;13:96. doi: 10.4103/abr.abr_101_23. eCollection 2024.
Elevated levels of atmospheric pollutants might disrupt the metabolism of vitamin D in the skin. Studies showed inconsistent results about the impact of air pollution on the serum vitamin D level. This study aims to systematically review the influence of air pollution on vitamin D levels.
The Medline database (PubMed), Web of Science, Scopus, and Google Scholar were systematically searched up to the end of July 2020. All observational, English-language, and human studies that assessed the effect of air pollution on vitamin D levels were included.
Among 432 studies, 26 papers were included in the systematic review and five studies in the meta-analysis. Exposure to air pollution was associated with lower vitamin D levels (pooled mean difference (MD) = -8.04, 95% confidence interval (CI): -10.34, -5.75). There was some evidence of heterogeneity between studies (I = 91.39%).
The findings revealed a reverse correlation between vitamin D levels and air pollution. Air pollutants have an impact on the penetration of solar ultraviolet B (UVB) to the Earth's surface. Consequently, the occurrence of vitamin D deficiency could be linked to air pollution.
大气污染物水平升高可能会扰乱皮肤中维生素D的代谢。关于空气污染对血清维生素D水平的影响，研究结果并不一致。本研究旨在系统评价空气污染对维生素D水平的影响。
截至2020年7月底，对Medline数据库（PubMed）、科学网、Scopus和谷歌学术进行了系统检索。纳入所有评估空气污染对维生素D水平影响的观察性、英文和人体研究。
在432项研究中，26篇论文被纳入系统评价，5项研究被纳入荟萃分析。接触空气污染与较低的维生素D水平相关（合并平均差（MD）=-8.04，95%置信区间（CI）：-10.34，-5.75）。研究之间存在一些异质性证据（I²=91.39%）。
研究结果揭示了维生素D水平与空气污染之间的负相关关系。空气污染物会影响太阳紫外线B（UVB）穿透地球表面。因此，维生素D缺乏的发生可能与空气污染有关。
